The contribution of human cortical area V3A to the perception of chromatic motion: a transcranial magnetic stimulation study.

The European Journal of Neuroscience
D J McKeefryA B Morland

Abstract

Area V3A was identified in five human subjects on both a functional and retinotopic basis using functional magnetic resonance imaging techniques. V3A, along with other visual areas responsive to motion, was then targeted for disruption by repetitive transcranial magnetic stimulation (rTMS) whilst the participants performed a delayed speed matching task. The stimuli used for this task included chromatic, isoluminant motion stimuli that activated either the L-M or S-(L+M) cone-opponent mechanisms, in addition to moving stimuli that contained only luminance contrast (L+M). The speed matching task was performed for chromatic and luminance stimuli that moved at slow (2 degrees/s) or faster (8 degrees/s) speeds. The application of rTMS to area V3A produced a perceived slowing of all chromatic and luminance stimuli at both slow and fast speeds. Similar deficits were found when rTMS was applied to V5/MT+. No deficits in performance were found when areas V3B and V3d were targeted by rTMS. These results provide evidence of a causal link between neural activity in human area V3A and the perception of chromatic isoluminant motion. They establish area V3A, alongside V5/MT+, as a key area in a cortical network that underpins the analysis of ...Continue Reading

References

Apr 1, 1978·The Journal of Physiology·S M Zeki
Sep 7, 1978·Nature·V S Ramachandran, R L Gregory
Jan 1, 1990·Experimental Brain Research·C GallettiP Fattori
Jan 1, 1989·Spatial Vision·P Cavanagh, G Mather
Jul 1, 1989·The Journal of Physiology·B B LeeA Valberg
Apr 1, 1987·Journal of Neurophysiology·D J Felleman, D C Van Essen
Feb 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·E H Adelson, J R Bergen
Dec 1, 1984·The Journal of Physiology·A M DerringtonP Lennie
Oct 1, 1994·Electroencephalography and Clinical Neurophysiology·D Rudiak, E Marg
Jun 22, 1995·Proceedings. Biological Sciences·D H FfytcheS Zeki
May 15, 1995·The Journal of Physiology·C F StromeyerR T Eskew
Sep 1, 1994·Journal of Neurophysiology·P DupontL Mortelmans
Feb 1, 1995·Brain : a Journal of Neurology·G Beckers, S Zeki
May 1, 1994·Visual Neuroscience·K R GegenfurtnerJ A Movshon
Oct 1, 1993·Vision Research·E J ChichilniskyB A Wandell
Jan 4, 1996·Nature·S J Cropper, A M Derrington
Mar 19, 1996·Proceedings of the National Academy of Sciences of the United States of America·E A DeYoeJ Neitz
Sep 1, 1996·Trends in Neurosciences·K R Gegenfurtner, M J Hawken
Apr 1, 1997·Journal of Neurophysiology·K R GegenfurtnerJ B Levitt
Apr 16, 1998·Vision Research·C L BakerK T Mullen
Apr 29, 1998·NeuroImage·D ChawlaK J Friston
May 21, 1999·The European Journal of Neuroscience·A ThieleK P Hoffmann
Jan 7, 2000·Neuron·R F DoughertyB A Wandell
Jan 7, 2000·Neuron·B A WandellL T Sharpe
Jan 7, 2000·Neuron·E SeidemannW T Newsome
Jun 1, 2000·Vision Research·T YoshizawaC L Baker
Mar 17, 2001·Nature Reviews. Neuroscience·V Walsh, A Cowey
Oct 31, 2001·Neuron·A ThieleT D Albright
Oct 31, 2001·Experimental Brain Research·N MatthewsS H Lisanby
Jan 1, 2003·Cerebral Cortex·S ZekiA Bartels
Mar 18, 2003·Vision Research·Tatsuya YoshizawaCurtis L Baker

❮ Previous
Next ❯

Citations

Feb 23, 2012·Brain Structure & Function·Milenko KujovicKatrin Amunts
Aug 29, 2013·Brain : a Journal of Neurology·Sharon Gilaie-DotanMarlene Behrmann
Jan 6, 2012·Journal of Neurophysiology·Hyun Ah Lee, Sang-Hun Lee
Jul 23, 2016·Neuropsychologia·Sharon Gilaie-Dotan
Jun 25, 2018·Brain Structure & Function·Nicolae SandaMichel Thiebaut de Schotten
Jan 12, 2021·Frontiers in Neuroscience·Junxiang LuoWei Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.