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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels

PLoS Genetics

Oct 17, 2012

Athma A PaiYoav Gilad

Abstract

Recent gene expression QTL (eQTL) mapping studies have provided considerable insight into the genetic basis for inter-individual regulatory variation. However, a limitation of all eQTL studies to date, which have used measurements of steady-state gene expression levels, is the inability...read more

Mentioned in this Paper

Metabolic Process, Cellular
BTG1 gene
Genome-Wide Association Study
Biochemical Pathway
Quantitative Trait Loci
T-Lymphocyte
Deoxyribonuclease I
Untranslated Regions
MiRNA Binding
Exons
4
1
157
Paper Details
References
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  • Citations36
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  • References77
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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels

PLoS Genetics

Oct 17, 2012

Athma A PaiYoav Gilad

PMID: 23071454

DOI: 10.1371/journal.pgen.1003000

Abstract

Recent gene expression QTL (eQTL) mapping studies have provided considerable insight into the genetic basis for inter-individual regulatory variation. However, a limitation of all eQTL studies to date, which have used measurements of steady-state gene expression levels, is the inability...read more

Mentioned in this Paper

Metabolic Process, Cellular
BTG1 gene
Genome-Wide Association Study
Biochemical Pathway
Quantitative Trait Loci
T-Lymphocyte
Deoxyribonuclease I
Untranslated Regions
MiRNA Binding
Exons
4
1
157

Similar Papers Found In These Feeds

Signal Transduction & Gene Expression (Keystone)

Tumor cells have their own unique signal transduction and gene expression control. Targeting these specific cellular mechanisms and genetic proflies of cancer cells is an area of therapeutic exploration for some cancers. Discover the latest research on this topic with this feed.

Eukaryotic RNA Polymerase II (Keystone)

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Related Papers

Paper Details
References
  • References77
  • Citations36
12345...
  • References77
  • Citations36
1234
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