PMID: 9440132Jan 24, 1998Paper

The contribution of synovial fluid lipoproteins to the chronic synovitis of rheumatoid arthritis

Prostaglandins
P E Prete, A Gurakar-Osborne

Abstract

Lipids in the synovial fluid of patients with active rheumatoid arthritis are elevated compared to normal synovial fluid and that of other inflammatory arthropathies. Various assumptions about the role of these lipids have been made. This study offers evidence that these lipids may contribute to the synovitis in rheumatoid arthritis through participation in the arachidonic pathway within the joint space. Phospholipase A2 activity, phospholipids, prostaglandin E2, and leukotriene B4 have been correlated in the synovial fluid and plasma of untreated rheumatoid patients and compared with that of patients with osteoarthritis.

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Citations

Jan 1, 2005·Indian Journal of Clinical Biochemistry : IJCB·D VijayakumarS Manoharan
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Apr 12, 2019·The Journal of Pharmacology and Experimental Therapeutics·Hirotomo ShimizuHiroshi Kuriyama

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