PMID: 589471Dec 9, 1977

The contribution of the contralateral labyrinth to second order vestibular neuronal activity in the cat

Brain Research
C H MarkhamI S Curthoys

Abstract

Vestibular brain stem units of the horizontal canal in the awake C1 transected cat were examined in acute experiments before and after the contralateral vestibular nerve was cut. The latter procedure resulted in an immediate increase in mean resting rate from 19 to 45 spikes/sec and greater spontaneous fluctuations in firing rate. Mean sensitivity to constant accelerations from 2 to 16 degrees/sec2 was significantly reduced. In the 4-6 degrees/sec2 range, for example, mean sensitivity fell from 5.7 +/- 3.2 spike/sec/deg/sec2 (range 0.7-13.6, n = 107) to 2.8 +/- 1.4 (range 0.2-5.5, n = 29). Mean sensitivity to 4-6 degrees/sec2 deceleration was reduced from about 4.5 to 3.0. On the other hand, time constants and the ratio of adapting to non-adapting units was unchanged. Removal of the midline cerebellum, including the vermis and fastigial nuclei in a portion of the animals, did not materially alter the above results. It is concluded that the contralateral labyrinth, acting via the vestibular brain stem commissural pathway, not only exerts a powerful effect on the resting activity of brain stem canal vestibular neurons, but also on their response to acceleration.

Citations

Jul 1, 1990·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·J G New
Apr 1, 1989·Brain Research. Brain Research Reviews·P F Smith, I S Curthoys
Feb 9, 1999·Neuroscience Research·J ItoS Mori
May 22, 1992·Annals of the New York Academy of Sciences·N FuruyaT Koizumi
Jul 7, 2009·Auris, Nasus, Larynx·T YagiKazuki Sugizaki
Mar 1, 1983·American Journal of Otolaryngology·R W BabinB F McCabe
Aug 10, 2010·Annals of Neurology·Peter zu EulenburgMarianne Dieterich
May 27, 2006·Brain Research·Michael S Jones, Michael Ariel
May 1, 1985·Acta Oto-laryngologica·E Fluur
Mar 21, 1998·Acta Oto-laryngologica·N Furuya, T Koizumi
May 1, 1979·Acta Oto-laryngologica·I S Curthoys
Jan 1, 1980·Acta Oto-laryngologica·S NakaoI S Curthoys
Jan 1, 1984·Acta Oto-laryngologica. Supplementum·C H Markham, T Yagi
May 10, 2016·Nature Communications·Diana E MitchellKathleen E Cullen
Mar 1, 1982·The Annals of Otology, Rhinology, and Laryngology·I S CurthoysC H Markham
Apr 1, 1980·The International Journal of Neuroscience·C Torda
Jun 1, 1985·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·T J Clegg, A A Perachio
Sep 1, 1984·Acta Oto-laryngologica·D L ClarkJ Bates
Jul 1, 1990·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·J G New, D Bodznick
Jun 27, 2017·Frontiers in Neurology·G M HalmagyiI S Curthoys
Aug 1, 1987·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·C H Markham
Oct 13, 2020·Journal of Vestibular Research : Equilibrium & Orientation·P F Smith
Jun 11, 2020·Cell Reports·Rachel A CareFelice A Dunn

Related Concepts

Nerve Impulses
Felis catus
Cerebellum
Membranous Labyrinth Structure
Ambidexterity
Neurons
Semicircular Canal Structure
Vestibular Nerve

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