The Controversy, Challenges, and Potential Benefits of Putative Female Germline Stem Cells Research in Mammals

Stem Cells International
Zezheng PanYuehui Zheng

Abstract

The conventional view is that female mammals lose their ability to generate new germ cells after birth. However, in recent years, researchers have successfully isolated and cultured a type of germ cell from postnatal ovaries in a variety of mammalian species that have the abilities of self-proliferation and differentiation into oocytes, and this finding indicates that putative germline stem cells maybe exist in the postnatal mammalian ovaries. Herein, we review the research history and discovery of putative female germline stem cells, the concept that putative germline stem cells exist in the postnatal mammalian ovary, and the research progress, challenge, and application of putative germline stem cells in recent years.

References

Dec 6, 1994·Proceedings of the National Academy of Sciences of the United States of America·Y FujiwaraT Noce
Oct 13, 2000·Science·T Xie, A C Spradling
Sep 22, 2001·Cell Structure and Function·T NoceN Tsunekawa
Jun 1, 1951·The Journal of Endocrinology·S H GREEN, S ZUCKERMAN
Mar 12, 2004·Nature·Joshua JohnsonJonathan L Tilly
Nov 16, 2005·Annual Review of Genetics·Marco D WongTing Xie
Jul 4, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·J B KerrJ K Findlay
Apr 13, 2007·Developmental Biology·Yifei LiuLin Liu
Apr 21, 2007·Science·Ralph L Brinster
May 18, 2007·Annual Review of Cell and Developmental Biology·Judith Kimble, Sarah L Crittenden
Dec 20, 2007·Reproductive Sciences·Dong ZhangAyman Al-Hendy
Jan 29, 2008·Current Stem Cell Research & Therapy·Antonin Bukovsky
May 3, 2008·Differentiation; Research in Biological Diversity·Irma Virant-KlunHelena Meden-Vrtovec
May 27, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Fariborz IzadyarFrancisco Silva
Jun 13, 2008·DNA and Cell Biology·Zhaojuan Yang, Ji Wu
Aug 30, 2008·Journal of Cellular Physiology·Yong Zhang, Ji Wu
Feb 9, 2010·Differentiation; Research in Biological Diversity·Jason PacchiarottiFariborz Izadyar
May 22, 2010·Science·Shuhei NakamuraMinoru Tanaka
Mar 27, 2012·Current Opinion in Cell Biology·Mark E GillAntoine H F M Peters
Apr 3, 2012·Current Opinion in Cell Biology·Manuel Irimia, Benjamin J Blencowe
Jul 11, 2012·Proceedings of the National Academy of Sciences of the United States of America·Hua ZhangKui Liu
Dec 19, 2012·Current Opinion in Cell Biology·Julia Promisel Cooper, Richard J Youle
Feb 15, 2013·Science Translational Medicine·Shiny TitusKutluk Oktay
Mar 14, 2013·BioMed Research International·Jung Jin LimDong Ryul Lee
May 1, 2013·Proceedings of the National Academy of Sciences of the United States of America·Lei Lei, Allan C Spradling
Oct 12, 2013·Journal of Cellular Physiology·Ying GuoZuping He

❮ Previous
Next ❯

Methods Mentioned

BETA
fluorescence-activated cell sorting
transgenic
flow cytometry
biopsy
scraping
genetic modification

Related Concepts

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Related Papers

Clinical Medicine Insights. Reproductive Health
Ayelet Evron, Zeev Blumenfeld
Health and Social Service Journal
S Burningham
© 2022 Meta ULC. All rights reserved