PMID: 9652318Jul 4, 1998Paper

The correlation between coronary stenosis index and flow-mediated dilation of the brachial artery

Japanese Circulation Journal
B KakuM Ohnaka

Abstract

We examined the relationship between flow-mediated dilation (FMD) of the brachial artery and the extent and severity of coronary artery disease (CAD). Using high-resolution ultrasonography, we measured FMD and nitroglycerin-induced brachial artery dilation. We studied 121 patients (77 men, 44 women; mean age 64+/-11 years, range 25-79 years) who underwent coronary arteriography. The extent and severity of CAD were assessed by the coronary stenosis index (CSI). The adjusted FMD correlated inversely with CSI (rs=-0.63, p<0.0001). Multivariate analysis demonstrated that the adjusted FMD was an independent predictor of CSI. The adjusted FMD was 10.2+/-4.8% in patients without CAD (n=32), 7.7+/-6.0% in patients with single-vessel disease (n=31), 5.2+/-5.5% in patients with double-vessel disease (n=29), and 2.0+/-3.9% in patients with triple-vessel disease (n=29). The adjusted FMD was significantly lower in the double- (p<0.01) and triple-vessel (p<0.0001) disease groups than in patients without CAD. The adjusted FMD was significantly lower in the triple-vessel disease group than in the single-vessel disease group (p<0.001). Based on our results, as coronary atherosclerosis becomes more severe, the adjusted brachial artery FMD become...Continue Reading

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Citations

May 18, 2001·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·K UeyamaM Ohnaka
Apr 7, 2006·Dynamic Medicine : DM·Devon A DobrosielskiUNKNOWN Louisiana Healthy Aging Study
Oct 12, 2001·Clinical Cardiology·R M Benitez, R A Vogel
Oct 1, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Seong-Mi ParkYoung-Moo Ro
Apr 21, 2007·Metabolism: Clinical and Experimental·Joanie B WilsonMichael Lefevre
Aug 16, 2005·Journal of the American College of Cardiology·Andrew SherwoodJames A Blumenthal
Apr 22, 2014·Expert Review of Cardiovascular Therapy·Ruth E HumphreysEllen A Dawson
Feb 27, 2014·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Agatino ManganaroGiuseppe Andò
Aug 1, 2006·Journal of Hypertension·Claudio FerriGuido Grassi
Mar 9, 2013·Medicine and Science in Sports and Exercise·Katharine D CurrieMaureen J MacDonald
Aug 5, 2017·The Journal of Spinal Cord Medicine·Daniel P CredeurDavid R Dolbow
Apr 7, 2009·Scandinavian Journal of Clinical and Laboratory Investigation·Line Skjold UlriksenGorm B Jensen
Dec 28, 2016·Clinical Physiology and Functional Imaging·Joseph D OstremDonald R Dengel

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