PMID: 15227734Jul 1, 2004Paper

The correlation between insulin resistance and the visceral fat to skeletal muscle ratio in middle-aged women

Yonsei Medical Journal
Chul Sik KimBong Soo Cha

Abstract

Central obesity with visceral fat accumulation and the amount of skeletal muscle mass may influence insulin sensitivity via its capacity for glucose load uptake. We investigated the relationships among the following metabolic variables: ratio of fat area to skeletal muscle area (VMR), percent ideal body weight, body mass index, waist-to-hip circumference (WHR) and visceral fat to subcutaneous fat ratio (VSR) in 114 nondiabetic middle-aged women. Anthropometric parameters, lipid profiles and sex hormone- binding globulin were measured. Visceral and subcutaneous fat areas at the umbilical level and the skeletal muscle area at the mid-thigh level were measured and computed. 75-gram OGTT tests were performed, along with measuring plasma glucose, insulin and free fatty acid levels, according to which area under the curve of glucose (Glu-AUC), insulin (Ins-AUC), free fatty acid (FFA-AUC) and glucose/insulin ratio (GIR=Glu- AUC/Ins-AUC), were calculated. 1) Triglyceride was more correlated with VSR than VMR. 2) The independent anthropometric parameters for each metabolic variable were In conclusion, VMR for Ins-AUC, WHR for Glu-AUC and total cholesterol, and VSR for triglyceride. 3) For subjects with higher VMR, age, Ins-AUC and trigl...Continue Reading

Citations

Nov 3, 2009·Journal of Gastroenterology·Yoichiro KitajimaKazuma Fujimoto
Jul 12, 2005·Current Medical Research and Opinion·Hussam AbuissaJames H O'keefe
Jul 22, 2011·Ultrasound in Medicine & Biology·Jisu OhYong-Wook Cho
Jun 1, 2007·Sleep Medicine Clinics·R Nisha Aurora, Naresh M Punjabi
Oct 15, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Jaividhya DasarathySrinivasan Dasarathy

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