The correlation between raised body mass index and assisted reproductive treatment outcomes: a systematic review and meta-analysis of the evidence

Reproductive Health
Prasanna Raj SupramaniamLee Nai Lim

Abstract

Public funding for fertility services within the United Kingdom is limited, and therefore, strict guidance exists regarding who can be offered treatment under the National Health Service (NHS). Body mass index (BMI) is a universal criteria adopted by both the public and private sector. This study addresses an important aspect of the impact of a raised BMI on fertility treatment outcomes. We standardise the analysis of the data by only including studies incorporating the WHO BMI criteria; the current reference point for clinicians and clinical commissioning groups in ascertaining which group of patients should receive treatment. This study is an update of the previous systematic review performed in 2010, with the inclusion of a larger number of cycles from central databases such as the Society for Assisted Reproductive Technology (SART). An electronic literature search was conducted through the Cochrane, Medline and Embase libraries. Data extraction for each outcome measure was pooled and expressed as an odds ratio with 95% confidence intervals. Where clinical heterogeneity was evident, the random effects model was used to calculate the risk ratio and a fixed effects model was used for the remaining studies. A p value < 0.05 was...Continue Reading

References

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Citations

Apr 26, 2019·Current Opinion in Obstetrics & Gynecology·Tanya GlennSteven R Lindheim
Jan 12, 2021·Frontiers in Endocrinology·Matteo CandeloroEttore Porreca
Jan 24, 2021·Gynécologie, Obstétrique, Fertilité & Sénologie·A PithoisJ-B Pretalli
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Dec 4, 2020·Fertility and Sterility·Mauro CozzolinoJose Bellver
Aug 28, 2021·Reproductive Biomedicine Online·Gemma FabozziFilippo Maria Ubaldi
Jun 5, 2019·American Journal of Obstetrics and Gynecology·Randi H GoldmanElizabeth S Ginsburg
Dec 17, 2021·Nature Reviews. Endocrinology·Niels E SkakkebækAnders Juul
Dec 18, 2021·Biology of Reproduction·Macarena B GonzalezRyan D Rose

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