The costs of epilepsy in Italy: a prospective cost-of-illness study in referral patients with disease of different severity

Epilepsy Research
A TettoOsservatorio Regionale per l'Epilessia (OREp)

Abstract

[corrected] Epilepsy poses a considerable economic burden on society. However, information is insufficient on the comparative costs of different disease varieties. The purpose of this study was to compare the direct costs of epilepsy in referral patients with disease of different severity and duration. Patients with newly diagnosed epilepsy (NDE), seizure remission (SR), occasional seizures (OS), frequent non-drug-resistant (NDR) and drug-resistant (DR) seizures, and surgical candidates (SC) from 14 epilepsy centers were the target population. All patients were followed prospectively for 12 months and all medical and paramedical contacts for diagnostic and therapeutic services were noted with details, using ad-hoc diaries and semistructured questionnaires. The study population comprised 525 consecutive children and adults with partial (68%), generalized (25%) and undetermined epilepsy (4%) as follows: NDE 70; SR 131; OS 108; NDR 101; DR 107; SC 8. Ambulatory visits (mean 2.8 per patient per year) were the leading service in all groups, followed by EEG recordings (1.8) and biochemical assays (1.1). At entry, the commonest drugs were carbamazepine (50%), valproate (37%), phenobarbital (21%), vigabatrin (14%) and lamotrigine (11%)...Continue Reading

Citations

May 10, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·I ForsgrenM Ekman
Sep 16, 2008·CNS Drugs·Ettore BeghiLivio Garattini
Feb 8, 2005·PharmacoEconomics·Ettore BeghiLivio Garattini
Dec 20, 2007·Epilepsia·Maura PugliattiPatrik Sobocki
Jun 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Demetris Pillas, Caroline Selai
Nov 27, 2015·BMC Neurology·Katharina AllersStephen Jan
Jun 13, 2002·Epilepsia·Charles E Begley, Ettore Beghi
Jul 12, 2007·Pharmazie in unserer Zeit·Richard DodelHajo Martinus Hamer
Dec 3, 2009·Expert Review of Neurotherapeutics·Tiziana GranataDamir Janigro
Oct 23, 2013·Epilepsia·Carlo Efisio MarrasUNKNOWN Commission on Epilepsy Surgery of the Italian League Against Epilepsy
Feb 18, 2009·Drugs & Aging·Massimiliano BeghiLivio Garattini
Sep 20, 2011·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Anders GustavssonUNKNOWN CDBE2010Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.