The costs of introducing artemisinin-based combination therapy: evidence from district-wide implementation in rural Tanzania.

Malaria Journal
Joseph D NjauAnne Mills

Abstract

The development of antimalarial drug resistance has led to increasing calls for the introduction of artemisinin-based combination therapy (ACT). However, little evidence is available on the full costs associated with changing national malaria treatment policy. This paper presents findings on the actual drug and non-drug costs associated with deploying ACT in one district in Tanzania, and uses these data to estimate the nationwide costs of implementation in a setting where identification of malaria cases is primarily dependant on clinical diagnosis. Detailed data were collected over a three year period on the financial costs of providing ACT in Rufiji District as part of a large scale effectiveness evaluation, including costs of drugs, distribution, training, treatment guidelines and other information, education and communication (IEC) materials and publicity. The district-level costs were scaled up to estimate the costs of nationwide implementation, using four scenarios to extrapolate variable costs. The total district costs of implementing ACT over the three year period were slightly over one million USD, with drug purchases accounting for 72.8% of this total. The composite (best) estimate of nationwide costs for the first thr...Continue Reading

References

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Citations

Nov 4, 2009·Cost Effectiveness and Resource Allocation : C/E·Nisso KasymovaBenusrat Sharipova
Mar 6, 2013·The American Journal of Tropical Medicine and Hygiene·Fabian M MashauriLeonard E G Mboera
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lais Pessanha de CarvalhoJana Held

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Methods Mentioned

BETA
IEC

Software Mentioned

ACT
Tz
IMPACT

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Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.