PMID: 18203085Jan 19, 2008Paper

The costs of treating glaucoma with combinations of topical drugs in Spain

European Journal of Ophthalmology
N NeymarkG Kobelt

Abstract

This study describes the treatment in ordinary clinical practice in Spain of patients with glaucoma with a two-drug combination therapy. The authors present the treatment outcome as endof-period intraocular pressure (IOP) and the calculated direct medical costs over a 2-year period. Data were extracted retrospectively from patient charts recording the use of all medical resources related to glaucoma. Costs were estimated using unit costs from public sources (2005). Descriptive cost analysis according to combination treatment at baseline was performed. The study included 216 patients from 21 centers. Around half of the patients were started on a beta-blocker/prostaglandin analogue combination, while the rest received various other combinations containing either an alpha2-agonist or a carbonic anhydrase inhibitor. Across the seven groups considered, there was a statistically significant difference in the costs of the least and the two most costly groups, while the confidence intervals were overlapping in all other pairwise comparisons. The least costly drug combination was brimonidine/timolol. Assessing IOP at the end of follow-up, all the groups were equally effective (overlapping confidence intervals). In a multivariate regress...Continue Reading

References

Oct 9, 2002·Archives of Ophthalmology·Anders HeijlUNKNOWN Early Manifest Glaucoma Trial Group
Jun 24, 2003·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·G K Krieglstein
Nov 26, 2005·Current Medical Research and Opinion·Stefan HolmstromMark Aagren

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Citations

Dec 23, 2016·Psychology & Health·Jorge Luis Méndez-Ulrich, Antoni Sanz
Aug 8, 2009·Journal of Glaucoma·Gisela KobeltJean-Philippe Nordmann
Apr 10, 2009·PharmacoEconomics·Richard G FiscellaJohn Walt
Feb 26, 2009·Current Opinion in Ophthalmology

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