The Counterweight programme: Prevalence of CVD risk factors by body mass index and the impact of 10% weight change

Obesity Research & Clinical Practice
M McQuiggS Radziwonik

Abstract

To examine relationships between body mass index (BMI), prevalence of physician-recorded cardiovascular disease (CVD) risk factors in primary care, and changes in risk with 10% weight change. The Counterweight Project conducted a baseline cross-sectional survey of medical records of 6150 obese (BMI ≥ 30 kg/m(2)), 1150 age- and sex-matched overweight (BMI 25 to <30 kg/m(2)), and 1150 age- and sex-matched normal weight (BMI 18.5 to <25 kg/m(2)) controls, in primary care. Data were collected for the previous 18 months to examine BMI and disease prevalence, and then modelled to show the potential effect of 10% weight loss or gain on risk. Obese patients develop more CVD risk factors than normal weight controls. BMI ≥ 40 kg/m(2) exhibits increased prevalence of type 2 diabetes mellitus (DM), odds ratio (OR) men: 6.16 (p < 0.001); women: 7.82 (p < 0.001) and hypertension OR men: 5.51 (p < 0.001); women: 4.16 (p < 0.001). Dyslipidaemia peaked around BMI 35 to <37.5 kg/m(2), OR men: 3.26 (p < 0.001); women 3.76 (p < 0.001) and CVD at BMI 37.5 to <40 kg/m(2) in men, OR 4.48 (p < 0.001) and BMI ≥ 40 kg/m(2) in women, OR 3.98 (p < 0.001). A 10% weight loss from the sample mean of 32.5 kg/m(2) reduced the OR for type 2 DM by 30% and CVD by...Continue Reading

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Citations

Oct 1, 2008·BMC Family Practice·Chiara DonfrancescoSimona Giampaoli
Jun 25, 2008·Journal of Health Services Research & Policy·UNKNOWN Counterweight Project Team
Dec 2, 2017·Annals of Surgery·Céline DuvoisinMichel Suter
Oct 24, 2019·Obesity Surgery·Abdelrahman Mohammad GalalJan Willem Greve
Feb 18, 2018·BMJ Open·Elizabeth A SturgissKirsty A Douglas
May 10, 2012·Journal of Perioperative Practice·Angela Cobbold, Sue Lord
May 30, 2019·JMIR MHealth and UHealth·Aroub AlnasserDebbi Marais
Sep 27, 2016·Journal of Veterinary Internal Medicine·M E PetersonM Rishniw

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