The course of cancer related fatigue up to ten years in early breast cancer patients: What impact in clinical practice?

The Breast : Official Journal of the European Society of Mastology
Alessandra FabiPatrizia Pugliese

Abstract

Little is known about the cancer related fatigue (CRF) along cancer course and risk factors that could predict CRF development and persistence in breast cancer (BC) survivors. This prospective study detected incidence, timing of onset, duration of CRF, impact on QoL and psychological distress. Seventy-eight early BC patients, undergoing chemotherapy (CT) followed or not by hormonal therapy were assessed for QoL and psychological distress by EORTC QLQC30 and HADs questionnaires. Fatigue was investigated with mix methods, structured interview and psychometric measures. A qualitative analysis was added to assess the behavioral pattern of CRF. Low fatigue levels were identified after surgery (9%), increasing during (49%) and at the end of CT (47%), maintaining after 1 year (31%) and declining up to ten years of follow-up. Prevalence of CRF was higher at the end of CT and lower at follow-up. At the end and after 1 and 2 years from CT, persistence of CRF was associated to anxiety in 20%, 11% and 5% and to depression in 15%, 10% and 5% respectively. A relationship between CRF and psychological distress was observed; patients presenting depression and anxiety before CT were at higher risk for fatigue onset at a later period. A relation...Continue Reading

Citations

Apr 24, 2018·Oncology Nursing Forum·Janine OvercashAnne M Noonan
Aug 8, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Fausto RoilaUNKNOWN NICSO (Network Italiano per le Cure di Supporto in Oncologia)
Jun 23, 2019·International Journal of Cancer. Journal International Du Cancer·Hélène PersonChristine Rotonda
Dec 18, 2019·Oncology Nursing Forum·Lena LeeGwenyth R Wallen
Jan 24, 2020·British Journal of Nursing : BJN·Osama Mohammad Abu-TahaMansour Saleh Alyami
Nov 1, 2018·Journal of Hospice and Palliative Nursing : JHPN : the Official Journal of the Hospice and Palliative Nurses Association·Kari Sand-Jecklin, Victoria Reiser
Feb 1, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Chang Wen-Pei, Jen Hsiu-Ju
Jun 20, 2020·Revista gaúcha de enfermagem·Eunice de Oliveira Lacerda Lima, Marcelle Miranda da Silva
Jun 9, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Eran Ben-AryeNoah Samuels
Apr 8, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·François GernierIdlir Licaj
Jan 5, 2021·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Shiao Li OeiFriedemann Schad
Mar 17, 2020·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A FabiUNKNOWN ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Aug 10, 2020·Journal of Pain and Symptom Management·Mohammed Al MaqbaliMu'ath Ibrahim Tanash
Sep 11, 2020·Medicine and Science in Sports and Exercise·Anouk E HienschHelene Rundqvist
Mar 2, 2021·British Journal of Nursing : BJN·Mohammed Al Maqbali
Sep 2, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Emily LamEdward Chow
Nov 21, 2021·Clinical Journal of Oncology Nursing·Mary RadomskiKaren K Swenson

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