The Course Of IGF-1 Levels and Nutrient Intake in Extremely and Very Preterm Infants During Hospitalisation

Nutrients
Dana F J YumaniMirjam M van Weissenbruch

Abstract

Insulin-like growth factor 1 (IGF-1) plays an important role in the complex association between nutrition, growth, and maturation in extremely and very preterm infants. Nevertheless, in this population, research on associations between IGF-1 and nutrition is limited. Therefore this study aimed to evaluate the possible associations between the course of IGF-1 levels and nutrient intake between preterm birth and 36 weeks postmenstrual age (PMA). 87 infants born between 24 and 32 weeks gestational age were followed up to 36 weeks PMA. Actual daily macronutrient intake was calculated, and growth was assessed weekly. IGF-1 was sampled from umbilical cord blood at birth and every other week thereafter. There was an inverse relationship between the amount of parenteral nutrition in the second week of life and IGF-1. Total protein, fat, and carbohydrate intake, as well as total energy intake, primarily showed a positive association with IGF-1 levels, particularly between 30 and 33 weeks PMA. Gestational age, bronchopulmonary dysplasia (BPD), and weight were significant confounders in the association between nutrient intake and IGF-1 levels. Parenteral nutrition was found to be a negative predictor of IGF-1 levels, and there could poten...Continue Reading

References

Apr 1, 1987·Current Problems in Pediatrics·R M Kliegman, M C Walsh
Mar 10, 1999·The American Journal of Physiology·M M WojnarC H Lang
Oct 3, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·V G KaklamaniC S Mantzoros
Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·A H Jobe, E Bancalari
Oct 31, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nesrin BesbasA Meguid El Nahas
Jul 13, 2005·Archives of Ophthalmology·UNKNOWN International Committee for the Classification of Retinopathy of Prematurity
Aug 11, 2006·European Journal of Clinical Nutrition·T NoratR Kaaks
Apr 3, 2012·Current Opinion in Clinical Nutrition and Metabolic Care·Anni LarnkjærKim F Michaelsen
Dec 29, 2012·European Journal of Pediatrics·Jolita BekhofIrma H L M Van Straaten
Mar 6, 2013·The Journal of Pediatrics·Alexandre Lapillonne, Ian J Griffin
Sep 2, 2014·BMC Pediatrics·Dominica A Gidrewicz, Tanis R Fenton
Jul 15, 2015·JAMA Pediatrics·Amish Jain, Prakesh S Shah
Jun 12, 2016·Archives of Disease in Childhood·Nicholas D EmbletonTimothy D Cheetham
Aug 16, 2016·The British Journal of Nutrition·Catherine BoyceGemma McLeod
Nov 12, 2016·Seminars in Perinatology·Krishnan MohanKumarAkhil Maheshwari
Feb 12, 2019·Open Access Macedonian Journal of Medical Sciences·Fatma A AlzareeTahany R Elias

❮ Previous
Next ❯

Methods Mentioned

BETA
PMA

Software Mentioned

SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Pediatric Gastroenterology and Nutrition
S C Ling
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
J P PeyratA Demaille
Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society
L TemmermanN Rosenthal
© 2021 Meta ULC. All rights reserved