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The CRISPR toolbox in medical mycology: State of the art and perspectives

PLoS Pathogens

Jan 17, 2020

Florent MorioGeraldine Butler

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PubMed

Abstract

Fungal pathogens represent a major human threat affecting more than a billion people worldwide. Invasive infections are on the rise, which is of considerable concern because they are accompanied by an escalation of antifungal resistance. Deciphering the mechanisms underlying virulence t...read more

Mentioned in this Paper

Codon (Nucleotide Sequence)
Complication
Genome
Biological Markers
Homologous Recombination
Candida (fungus)
Fungi
Drug Resistance
Transformation, Genetic
Genes
64
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© 2020 Meta ULC. All rights reserved

The CRISPR toolbox in medical mycology: State of the art and perspectives

PLoS Pathogens

Jan 17, 2020

Florent MorioGeraldine Butler

PMID: 31945142

DOI: 10.1371/journal.ppat.1008201

Abstract

Fungal pathogens represent a major human threat affecting more than a billion people worldwide. Invasive infections are on the rise, which is of considerable concern because they are accompanied by an escalation of antifungal resistance. Deciphering the mechanisms underlying virulence t...read more

Mentioned in this Paper

Codon (Nucleotide Sequence)
Complication
Genome
Biological Markers
Homologous Recombination
Candida (fungus)
Fungi
Drug Resistance
Transformation, Genetic
Genes
64

Feeds With Similar Papers

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Related Papers

Paper Details
References
  • References100
  • Citations
12345...
  • References100
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Download from

Publisher
PubMed
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