PMID: 9181553Apr 1, 1997Paper

The CUB domains of procollagen C-proteinase enhancer control collagen assembly solely by their effect on procollagen C-proteinase/bone morphogenetic protein-1

Matrix Biology : Journal of the International Society for Matrix Biology
David J S HulmesE Kessler

Abstract

Procollagen C-proteinase enhancer (PCPE) is a 55 kDa glycoprotein that increases the activity of procollagen C-proteinase (PCP)/bone morphogenetic protein-1 (BMP-1) during C-terminal processing of fibrillar collagen precursors. Here we show that the 36 kDa, active fragment of PCPE enhances the activity of both the short (mouse) and long (chick) forms of PCP/BMP-1. The activity of PCPE is not associated with the formation of sedimentable procollagen aggregates. In addition, PCPE (36 kDa) has no effect in vitro on N-terminal procollagen processing by highly purified procollagen N-proteinase. Finally, when the amount of PCP is adjusted so that the rate of C-terminal processing remains constant, PCPE (36 kDa) has no effect on the assembly of collagen or pN-collagen in vitro following C-terminal processing of the corresponding precursors.

References

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Citations

Mar 23, 2000·Journal of Hepatology·D A BrennerR A Rippe
Dec 12, 2003·Matrix Biology : Journal of the International Society for Matrix Biology·Nina G HallSuneel S Apte
Oct 6, 2009·The Journal of Biological Chemistry·Daniel KronenbergCatherine Moali
Sep 24, 2011·The Journal of Biological Chemistry·Sandrine Vadon-Le GoffCatherine Moali
Jul 16, 2010·The Journal of Investigative Dermatology·Daniel KronenbergChristoph Becker-Pauly
Oct 7, 2014·The International Journal of Biochemistry & Cell Biology·Tali WeissEfrat Kessler
Feb 24, 2015·Matrix Biology : Journal of the International Society for Matrix Biology·Sandrine Vadon-Le GoffCatherine Moali
Sep 18, 2004·The Journal of Investigative Dermatology·Ryan F L O'ShaughnessyAngela M Christiano
Jan 24, 2002·The Journal of Biological Chemistry·Satoshi HirohataSuneel S Apte
Aug 3, 2005·The Journal of Biological Chemistry·Nathan V LeeM Luisa Iruela-Arispe
Jan 8, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mourad BekhoucheAlain Colige
Dec 18, 2002·The Journal of Biological Chemistry·Simonetta BernoccoDavid J S Hulmes
May 29, 2019·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Ofra GoharEfrat Kessler
Feb 28, 2018·Growth Factors·Lovorka GrgurevicSlobodan Vukicevic
Jul 10, 2002·The Journal of Biological Chemistry·Sylvie Ricard-BlumDavid J S Hulmes
May 13, 2004·The Journal of Biological Chemistry·Nicole PischonPhilip C Trackman
Jan 13, 2006·The Journal of Biological Chemistry·Weiting GeShu Zheng
Apr 5, 2018·Journal of Developmental Biology·Dominique ManikowskiKay Grobe
Apr 15, 2003·Journal of Cell Science·Caroline M Milner, Anthony J Day

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