The cutoff point of clinical chronic obstructive pulmonary disease questionnaire for more symptomatic patients

BMC Pulmonary Medicine
Yong Suk JoChang-Hoon Lee

Abstract

An adequate threshold for the Clinical Chronic Obstructive Pulmonary Disease (COPD) Questionnaire (CCQ) defining more symptomatic COPD patients has not been determined. We aimed to determine the efficacy of the CCQ and the appropriate CCQ threshold for more symptomatic COPD patients. COPD patients aged > 40 years who smoked/had smoked ≥10 packs/year were prospectively enrolled over 1 year from three South Korean hospitals (n = 126). Correlations between the CCQ and St. George's Respiratory Questionnaire (SGRQ), COPD Assessment Test (CAT), the modified Medical Round Council (mMRC) scale, lung function, and exercise capacity were evaluated. "More symptomatic patients" were those with an SGRQ score ≥ 25. Area under the receiver operating curve and classification and regression tree analyses were performed to determine the CCQ threshold equivalent to an SGRQ score ≥ 25. The CCQ significantly correlated with the SGRQ, CAT, and mMRC scale (r = 0.76, 0.69, and 0.53, respectively). A CCQ cutoff of 1.4 predicted an SGRQ score of 25 better than others. A CCQ score of 1.4 was a significant determinant of an SGRQ score ≥ 25 even after adjusting for potential confounders. The CCQ was correlated with other symptom indicators, lung function, ...Continue Reading

Associated Clinical Trials

Aug 19, 2015·Chang-Hoon Lee

References

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Citations

Nov 20, 2020·The Clinical Respiratory Journal·Mariana Pereira FloresValéria Amorim Pires Di Lorenzo
Mar 25, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Åsa AthlinJosefin Sundh
Oct 12, 2021·Pulmonology·I LadeiraM Guimarães
Jul 14, 2020·Respiration; International Review of Thoracic Diseases·Zijing ZhouPing Chen

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Clinical Trials Mentioned

NCT02527486

Software Mentioned

STATA

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