PMID: 9162405Jan 1, 1996Paper

The cytogenesis and differentiation of the epithelial endocrinocytes of the large intestine in hens and rats in ontogeny

Morfologi︠a︡
O V Ivanova, A A Puzyrev

Abstract

Cytogenesis and differentiation of epithelial endocrinocytes were studied by methods of histochemistry and electron microscopy in large intestine of hen and rat in the course of their individual development. In the embryogenesis processes of cellular and organospecific differentiation occur in epithelium of these animals large intestine, which is proved by early revealing of endocrinocytes, when epithelial plast is yet undifferentiated. Growth of differentiation in hen and rats is marked on day 19-21 of postnatal embryonal development. In postnatal ontogenesis endocrine apparatus achieves definitive state by day 5 in hen and day 20 in rats. Argentaffin cells are the leading sub-population, which reflects the importance of serotonine they produce in realizing regulatory reactions of the organism. Slightly differentiated cells are the source of endocrinocyte cytogenesis.

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