The cytologic composition of dacryops: an immunohistochemical investigation of 15 lesions compared to the normal lacrimal gland

American Journal of Ophthalmology
Frederick A JakobiecLynn P Perry

Abstract

To define the cytologic composition of the double-layered epithelial lining of dacryops (lacrimal duct cyst), improve histopathologic diagnosis, and better understand pathogenesis. Clinicopathologic retrospective study with immunohistochemical studies of 15 lesions compared with normal lacrimal gland. Clinical data from 14 patients were reviewed and microscopy was performed with routine stains and immunohistochemical probes for epithelial membrane antigen (EMA), gross cystic disease fluid protein-15 (GCDFP-15), cytokeratin 7 (CK7), and smooth muscle actin (SMA). The major lacrimal gland was involved in 13 lesions; 2 lesions arose in an accessory gland of Krause. One case was bilateral; the average age of the patients was 50.7 years. Neither visual acuity nor motility was disturbed. No lesion was discovered to have recurred after excision. Microscopically, in all dacryops specimens goblet cells and luminal pseudoapocrine apical cytoplasmic projections were identified. Lacrimal acinar cells immunoreacted with GCDFP-15 and CK7, whereas the normal ducts and the epithelium of the dacryops lesions reacted diffusely only with CK7. SMA-positive myoepithelial cells were found in the acini but not in the normal ducts or dacryops epitheli...Continue Reading

References

May 1, 1978·Archives of Ophthalmology·B D SrinivasanA G DeVoe
Aug 1, 1978·Archives of Ophthalmology·Frederick A JakobiecJ Sigelman
May 1, 1992·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·T Kivelä
Oct 1, 1992·Ophthalmology·R G Weatherhead
Nov 1, 1988·Ophthalmic Surgery·S T Conway
Aug 1, 1988·Archives of Ophthalmology·J A NeradR Folberg
Oct 1, 1986·Ophthalmology·J D BullockJ S Rosset
Jan 1, 1974·Archives of Ophthalmology·L M JampolM Tyler
Jan 1, 1970·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·M Radnót, K Lapis
Jan 1, 1967·American Journal of Ophthalmology·D K Sen, A Thomas
Dec 1, 1983·Ophthalmology·K SternW G Harrison
Nov 1, 1984·Ophthalmology·S BrownsteinF Codere
Jul 1, 1983·The British Journal of Ophthalmology·J A Durán, J Cuevas
Aug 1, 1981·American Journal of Ophthalmology·A Rush, C R Leone
Jul 1, 1995·The British Journal of Ophthalmology·A Padwell
Jan 1, 1995·American Journal of Ophthalmology·D B ChristieM Lahav
Feb 1, 1994·The American Journal of Dermatopathology·S C van der Putte
Nov 1, 1995·The British Journal of Ophthalmology·H D Remulla, P A Rubin
May 1, 1997·Australian and New Zealand Journal of Ophthalmology·J A WestAlan A McNab
Jan 11, 2001·Ophthalmology·C E Margo, H E Grossniklaus
Feb 24, 2001·Ophthalmic Plastic and Reconstructive Surgery·W J Rosen, Y Li
Nov 9, 2002·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·S M BethariaSeema Sen
Dec 24, 2004·AJR. American Journal of Roentgenology·Apostolos John TsiourisBrian G Brazzo
Feb 18, 2005·Acta Ophthalmologica Scandinavica·Ghassan Ayish AlyahyaSteffen Heegaard
Mar 22, 2006·Ophthalmic Plastic and Reconstructive Surgery·J J DuttonAlan D Proia
May 23, 2009·Clinical & Experimental Ophthalmology·Jaime LevyJacob Pe'er
Jul 3, 2009·Journal of the American Animal Hospital Association·Juri OtaElizabeth A Giuliano
May 27, 2010·Ophthalmic Plastic and Reconstructive Surgery·Frederick A JakobiecThomas M Kropp
Aug 11, 2010·Cornea·Frederick A JakobiecKathryn A Colby
Dec 21, 2010·American Journal of Ophthalmology·Frederick A Jakobiec, Fouad R Zakka
Feb 2, 2011·Ophthalmic Plastic and Reconstructive Surgery·Peter J TimoneyDavid E Cowen
May 11, 2011·Archives of Ophthalmology·Anna Bartoletti-StellaGiuseppe Gasparre
Jul 15, 2011·Journal of Cutaneous Pathology·Denisa KacerovskaDmitry V Kazakov
Dec 3, 2011·Orbit·Alejandra A Valenzuela, J Godfrey Heathcote
Feb 15, 2012·Archives of Ophthalmology·Andre JastrzebskiJoseph de Nanassy
Apr 25, 2012·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Richard M RobbCaroline D Robson
Mar 14, 2013·Annals of Maxillofacial Surgery·Header D Al-MualaAbbas T Alaboudy

Citations

Feb 20, 2016·Survey of Ophthalmology·Frederick A JakobiecRalph C Eagle
Aug 14, 2013·American Journal of Ophthalmology·Michael K YoonPia R Mendoza
Dec 24, 2013·Survey of Ophthalmology·Aristomenis ThanosMark P Hatton
Mar 21, 2015·Ophthalmic Plastic and Reconstructive Surgery·Frederick A JakobiecKathryn A Colby
Jan 8, 2015·Ophthalmic Plastic and Reconstructive Surgery·Frederick A JakobiecAaron Fay
Oct 31, 2014·Cornea·Frederick A JakobiecMichael K Yoon
Oct 12, 2017·Taiwan Journal of Ophthalmology·Gautam LokdarshiMandeep S Bajaj
Jan 10, 2020·Orbit·Hamad M AlsulaimanSilvana Artioli Schellini
Sep 26, 2020·BMC Ophthalmology·Yu ZhangChunling Liu
Oct 10, 2020·Veterinary Ophthalmology·Federica Maggio
Jan 15, 2021·Veterinary Ophthalmology·Andrea SteinmetzChristoph Mülling
Sep 22, 2020·The American Journal of Dermatopathology·Parth R VaidyaDouglas J Grider
Feb 2, 2020·American Journal of Ophthalmology·Frederick A JakobiecCarol Shields

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