PMID: 3751556Jul 1, 1986Paper

The daytime breath hydrogen profile in children with abdominal symptoms and diarrhoea

Acta paediatrica Scandinavica
C M KneepkensJ Fernandes

Abstract

The daytime breath hydrogen profile (DBHP) enables the study of breath hydrogen (BH) excretion in children under normal dietary and environmental circumstances. We studied the DBHP in 43 children with abdominal pain and (or) diarrhoea in order to evaluate its use in the detection of carbohydrate malabsorption (CHM). The results were compared to those of the lactose BH test. The DBHP was abnormal in 16 patients (37%), 8 of whom also had an abnormal lactose BH test. Five other patients with an abnormal lactose BH test had a normal DBHP. In 7 out of 10 children with an abnormal DBHP, the recorded abdominal symptoms coincided with a sharp increase in BH excretion. Abnormal DBHPs were most frequently found in children with functional abdominal complaints and with giardiasis. Our findings indicate that CHM is more frequently encountered in children with abdominal symptoms than can be detected by the lactose BH test. The DBHP offers new possibilities in the investigation of gastrointestinal conditions by correlating the symptoms directly to the effect induced by CHM.

References

Apr 1, 1978·The American Journal of Clinical Nutrition·J FernandesH J Degenhart
Jun 28, 1979·The New England Journal of Medicine·R G BarrJ B Watkins
Oct 1, 1978·The American Journal of Clinical Nutrition·J H Bond, M D Levitt
Apr 30, 1985·Clinica Chimica Acta; International Journal of Clinical Chemistry·C M KneepkensJ Fernandes
Jun 1, 1982·The Journal of Nutrition·D Marthinsen, S E Fleming
Jan 5, 1984·The New England Journal of Medicine·J C KolarsD A Savaiano
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Aug 1, 1984·Archives of Disease in Childhood·C M KneepkensJ Fernandes
Jun 20, 1981·British Medical Journal·I BlumenthalJ M Littlewood
Jan 1, 1982·The Journal of Pediatrics·A WaldB Zitelli
Apr 9, 1981·The New England Journal of Medicine·I H AndersonM D Levitt

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Citations

Apr 1, 1989·European Journal of Pediatrics·C M KneepkensA C Douwes

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