The demographics and geographic distribution of laboratory-confirmed Lyme disease cases in England and Wales (2013-2016): an ecological study

BMJ Open
John S P TullochJenny C Warner

Abstract

Lyme disease is a tick-borne disease of increasing incidence and public concern across the Northern Hemisphere. However, the socio-demographics and geographic distribution of the population affected in England and Wales are poorly understood. Therefore, the proposed study was designed to describe the demographics and distribution of laboratory-confirmed cases of Lyme disease from a national testing laboratory. An ecological study of routinely collected laboratory surveillance data. Public Health England's national Lyme disease testing laboratory. 3986 laboratory-confirmed cases of Lyme disease between 2013 and 2016. In England and Wales, the incidence of laboratory-confirmed Lyme disease rose significantly over the study period from 1.62 cases per 100 000 in 2013 to 1.95 cases per 100 000 in 2016. There was a bimodal age distribution (with peaks at 6-10 and 61-65 years age bands) with a predominance of male patients. A significant clustering of areas with high Lyme disease incidence was located in southern England. An association was found between disease incidence and socioeconomic status, based on the patient's resident postcode, with more cases found in less deprived areas. Cases were disproportionately found in rural areas ...Continue Reading

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Citations

Mar 11, 2020·Medicina·Agnė PetrulionienėAlgirdas Venalis
Jul 9, 2020·BJGP Open·John Sp TullochRob M Christley
Aug 1, 2019·BMJ Open·Victoria CairnsCarlos Martinez
Oct 12, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Karina M FordeMichael J O'Grady
Jan 27, 2021·Emerging Infectious Diseases·Caroline MillinsRoman Biek
Jun 15, 2021·Experimental & Applied Acarology·Kayleigh M HansfordJolyon M Medlock
Jul 3, 2021·Brain Sciences·Sylwia KozakJustyna Paprocka

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Software Mentioned

Exploratory spatial data analysis ( ESDA )
R
R Core Team

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