PMID: 7026797Jan 1, 1981Paper

The density distribution of gene loci over the genetic map of Escherichia coli: its structural, functional and evolutionary implications

Journal of Molecular Evolution
D A De Martelaere, A P Van Gool

Abstract

A quantitative analysis was carried out on the dispersion of gene loci over the E. coli genetic map. Therefore, the map was divided into regions characterized by an homogeneous gene density. This created a distribution pattern of gene loci that contained a symmetry axis located near to the origin of DNA replication. The pattern could be subdivided into a set of 22 functional domains containing gene loci whose products revealed a biochemical or functional relatedness. A correlation was found between the boundary positions of these domains and the distribution of F plasmid- and DNA insertion sites over the E. coli chromosome. The structural, functional and evolutionary implications of these findings are discussed.

References

May 1, 1979·Journal of Bacteriology·E Mathys, A Van Gool
Jan 1, 1978·Annual Review of Genetics·K B Low, D D Porter
May 12, 1978·Journal of Molecular Evolution·M RileyD Zipkas
Jun 1, 1978·Molecular & General Genetics : MGG·O Fayet, J M Louarn
Aug 1, 1978·Journal of Bacteriology·E C Materman, A P Van Gool
Jan 1, 1978·Annual Review of Microbiology·M Riley, A Anilionis
Dec 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·K Isono, M Kitakawa
Nov 9, 1978·Molecular & General Genetics : MGG·R C Marsh
Apr 17, 1979·Molecular & General Genetics : MGG·J LouarnJ M Louarn
Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·D Zipkas, M Riley

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Citations

Mar 10, 2004·Bulletin of Mathematical Biology·R E SveticJ H Jackson
Apr 3, 2007·BMC Bioinformatics·Michael C RileyRoss D King
Dec 26, 2009·BMC Systems Biology·Nikolaus SonnenscheinDietrich Stoyan
Sep 10, 2003·Journal of Molecular Biology·Benjamin Audit, Christos A Ouzounis

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