The dependence of the latency relaxation on temperature in single muscle fibres of the frog

Acta Physiologica Scandinavica
P Haugen

Abstract

The time course of the latency relaxation was studied at various temperatures in the range 0-26 degrees. Over the entire range the time of onset of the drop in tension, t1, was independent of sarcomere length. At temperatures above 12-15 degrees C the falling phase had a point of inflexion, while at lower temperatures there was an interval during which the tension fell at a constant rate. The time when the rate of drop in tension had passed its maximum value tL2, the time to the maximum drop in tension t2, and the time when the tension crossed the resting level t3, all showed linear dependence on sarcomere length in the range from 2.1 to 2.7-3.4 microgram. In this range the durations of the intervals tL2-t1, t2-t1, and t3-t1 were nearly proportional to the distance from the Z-line to the end of the zone of overlap between the thick and the thin filaments. This could be explained as the activation being a longitudinal process starting from the Z-line. The slopes (dt/dS) of the linear portions of the time variables t1.2, t2, and t3 in a time-sarcomere length (S) diagram all had the same dependence on temperature giving a Q10 of 1.75. Under the assumption that the activation process followed a diffusion of calcium from the Z-line ...Continue Reading

References

Sep 1, 1976·The Journal of General Physiology·P Haugen, O Sten-Knudsen
Dec 1, 1969·The Japanese Journal of Physiology·M Matsumura
Apr 12, 1972·Nature: New Biology·P J VibertF R Poulsen
Nov 28, 1972·Journal of Molecular Biology·P J VibertF R Poulsen
Jan 1, 1968·Progress in Biophysics and Molecular Biology·S Ebashi, M Endo
Dec 5, 1969·Science·M J Kushmerick, R J Podolsky
Jan 1, 1970·The Journal of General Physiology·S Winegrad
May 1, 1966·The Journal of Physiology·A M GordonF J Julian
Mar 21, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S Ebashi
Jun 1, 1981·Acta Physiologica Scandinavica·P Haugen, O Sten-Knudsen

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Citations

Oct 26, 2010·Progress in Biophysics and Molecular Biology·N Yagi
Feb 1, 1990·Pflügers Archiv : European journal of physiology·P J GriffithsC C Ashley

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