The development of a reference database with the Topcon 3D OCT-1 Maestro

Clinical Ophthalmology
Michael ChaglasianCharles A Reisman

Abstract

The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Prospective, multicenter cohort study conducted at 7 clinical sites across the USA. Primary eyecare clinics within academic, hospital, and private practice locations. Healthy volunteers; all enrolled participants underwent a complete ophthalmological examination to confirm healthy ocular status prior to being enrolled in the study. Average and 1st, 5th, 95th, and 99th percentile ranges for OCT parameters Early Treatment Diabetic Retinopathy Study macula full retinal thickness, ganglion cell + inner plexiform layer thickness (GCL + IPL), ganglion cell complex (GCC) thickness, circumpapillary retinal nerve fiber layer (cpRNFL) thickness. Three hundred and ninety-nine eyes of 399 subjects were included in the analysis. Mean (SD) age was 46.3 (16.3) years (range 18-88 years). Forty-three percent of the subjects were male. Mean (SD) measurements (in μm) for the 12×9 mm wide scan were as follows: foveal thi...Continue Reading

Clinical Trials Mentioned

NCT02447120

Software Mentioned

IntegReview
Topcon
TSNIT
R
Fastmap
OCT Maestro

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