PMID: 8440087Jan 1, 1993Paper

The development of Pneumocystis carinii pneumonia in germ-free rats requires immunosuppression and exposure to the Pneumocystis carinii organism

Comparative Immunology, Microbiology and Infectious Diseases
L WolffD Gemsa

Abstract

Adult germ-free rats treated with dexamethasone and exposed to a non-sterile environment did not harbor or develop Pneumocystis carinii cysts or trophozoites after 10 weeks of immunosuppression. Only when they were exposed to infected, conventional rats and treated with dexamethasone for 8 weeks or longer, did adult germ-free rats develop P. carinii infection.

References

Jun 1, 1979·Experimental Parasitology·P D WalzerB J Stahr
Oct 1, 1984·The Journal of Infectious Diseases·L L Pifer
Jan 1, 1984·Diagnostic Microbiology and Infectious Disease·L L PiferD R Owens
Mar 1, 1983·The Journal of Infectious Diseases·W T HughesB M Smith
Jun 1, 1982·The Journal of Infectious Diseases·W T Hughes

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Citations

Feb 5, 2002·Microbes and Infection·Alison MorrisLaurence Huang
Nov 19, 2008·The Journal of Infectious Diseases·Heather M KlingKaren A Norris
Apr 12, 2012·Clinical Microbiology Reviews·Alison Morris, Karen A Norris
Nov 9, 2000·American Journal of Respiratory and Critical Care Medicine·A M MorrisL Huang
Aug 26, 2014·Annals of the American Thoracic Society·M Patricia GeorgeJohn F McDyer
Sep 5, 2013·The Journal of Eukaryotic Microbiology·Peter D Walzer
Sep 26, 2000·The Korean Journal of Parasitology·B S ChungS T Hong

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