The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder.

Neurourology and Urodynamics
Alan D UrenPaul Abrams

Abstract

To present the development of the International Consultation on Incontinence Questionnaire-underactive bladder (ICIQ-UAB) as the first patient reported outcome measure for the assessment of the symptoms and impact on the health-related quality of life of UAB developed in-line with the Food and Drug Administration Guidance for Industry. Draft items were developed following 44 semi-structured concept elicitation interviews in the UK and refined using 36 cognitive interviews. A pilot study was designed to assess the draft ICIQ-UAB's initial psychometric properties with 54 patients recruited from European hospitals. Further concept elicitation interviews were also carried out with 11 patients in the US and 10 patients in Japan. All participants had a prior urodynamic diagnosis of detrusor underactivity. The cognitive interviews confirmed the initial items to be understood and interpreted as intended. Pilot testing showed that both internal consistency (Cronbach's α ≥ 0.85) and test-retest reliability (stable patients; intraclass correlation coefficient ≥ 0.88) were high. The interviews in the US and Japan elicited symptoms and impacts that support previous findings in the UK and provided further insight into the experiences of pati...Continue Reading

References

Feb 22, 2002·Neurourology and Urodynamics·Paul AbramsUNKNOWN Standardisation Sub-committee of the International Continence Society
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Apr 5, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Diane WildUNKNOWN ISPOR Task Force for Translation and Cultural Adaptation
Feb 14, 2006·The Journal of Urology·Paul AbramsUNKNOWN ICIQ Advisory Board
Jan 10, 2008·Research in Nursing & Health·Melody A Hertzog
Jan 5, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Bryce B ReeveZeeshan Butt
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Dec 2, 2015·International Neurourology Journal·Nathan Hoag, Johan Gani
Feb 25, 2017·International Urology and Nephrology·Karel DewulfMichael B Chancellor
Apr 13, 2017·European Urology·Alan D UrenPaul Abrams
Sep 12, 2018·Neurourology and Urodynamics·Christopher R ChapplePaul Abrams

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