The development of topographical maps and fibre types in toad (Bufo marinus) glutaeus muscle during synapse elimination

The Journal of Physiology
M R BennettA W Everett

Abstract

1. The toad glutaeus muscle consists of two muscle compartments. A study has been made of the topographical distribution of motor units in these compartments, in relation to the fibre types which arise during different stages of development. 2. Monoclonal antibodies to myosin allowed the distribution of fibre types to be determined. In mature muscles (from toads of greater than 30 g body weight) clusters of type 5 (tonic) fibres were found exclusively at the dorsal surface of the muscle, surrounded by a layer of type 3 (slow-twitch) fibres. A homogeneous layer of type 2 (fast-twitch red) fibres was found beneath this dorsal rind of slow and tonic fibres. The rest of the muscle, including the ventral surface, consisted of a mosaic of type 1 (fast-twitch white) and type 2 fibres. 3. Glycogen-depletion methods, together with the myosin antibodies, allowed the distribution of single motor units and their fibre types to be determined. In mature muscles, axons originating from rostral spinal cord possessed muscle units located in a band extending from the ventral surface to beyond the middle of the muscle; these units consisted of 78% type 1 and 22% type 2 fibres found amongst the mosaic of type 1 and type 2 fibres. Intermediate axon...Continue Reading

Citations

Dec 7, 2006·BMC Infectious Diseases·Arni S R Srinivasa RaoChris T Bauch
Jan 22, 1991·The Journal of Comparative Neurology·G S BewickN Holder
Jan 16, 1995·The Journal of Comparative Neurology·K S Cramer, D C Van Essen
Jul 15, 2015·Journal of Neurophysiology·Taian M VieiraEmma F Hodson-Tole
Mar 4, 1996·The Journal of Comparative Neurology·A W Everett, D R Brown

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