The Diagnosis and Treatment of Pacemaker-Associated Infection

Deutsches Ärzteblatt International
Michael DöringGerhard Hindricks

Abstract

Approximately 105 000 cardiac electronic devices are newly implanted in Germany each year. Germany has the highest implantation rate with respect to population of any European country. Infections in cardiac implants are serious complications, with an associated in-hospital mortality of 5-15%. It is thus very important to optimize the diagnostic and therapeutic strategies by which such infections can be detected early and treated effectively. This review is based on pertinent publications retrieved by a search in PubMed, with special attention to the current recommendations of international medical specialty societies. According to the international literature, the incidence of device-associated infection is 1.7% (in six months) for implanted defibrillators and 9.5% (in two years) for resynchronization devices. No absolute figures on infection rates are available for Germany. Infection can involve either the site where the impulse generator is implanted or the intravascular portion of the electrodes. The most important elements of the diagnostic evaluation are: assessment of the local findings; pathogen identification by culture of peripheral blood, swabs of the infected site, or material recovered at surgery; and transesophagea...Continue Reading

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Citations

Jun 14, 2019·QJM : Monthly Journal of the Association of Physicians·O M P Jolobe
Jul 24, 2020·Journal of the American Heart Association·Hezzy ShmueliRobert J Siegel
Nov 28, 2018·Deutsches Ärzteblatt International·Hartmut Dunkelberg
Nov 28, 2018·Deutsches Ärzteblatt International·Michael Döring
Feb 2, 2021·Curēus·Venkataramana Kandi, Sabitha Vadakedath
Mar 23, 2021·Frontiers in Medicine·Aurelia KimmigMathias W Pletz

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