PMID: 11327086May 1, 2001Paper

The diagnosis of bacterial vaginosis and vaginal flora changes

Archives of Gynecology and Obstetrics
D HellbergP A Mårdh

Abstract

In a population of 956 women, attending for contraceptive advice, 131 (13.7%) were found to have BV acording to Amsel's criteria. Clue cells were detected in 200 (20.9%) women, a positive amine ('sniff') test in 191 (20.0%), a vaginal pH > or = 4.7 in 243 (25.4%) and a "characteristic" vaginal discharge in 104 (10.9%) women. Sensitivity, specificity, positive and negative predictive values in relation to BV were calculated for each of these four criteria. The detection of clue cells, an increased pH and a positive sniff test showed excellent sensitivity (86-100%) values, but had a less satisfactory positive predictive value (52-68%). Vaginal discharge was found to be a poor predictor of BV. The vaginal flora in women with clue cells, increased vaginal pH or a positive sniff test was very similar to that of the women with BV, every after excluding concomitant cases of BV and the three respective criteria. Thus, a positive amine test, which is easily performed, strongly suggests BV and a vaginal flora predominated by Gardnerella vaginalis, Mycoplasma hominis, Mobiluncus species and anaerobic species on one hand, and lack of lactobacilli on the other. When there is a clinical suspicion of BV, the sniff test is positive and differe...Continue Reading

Citations

Jun 5, 2007·Maternal and Child Health Journal·Deborah B NelsonFrank K Friedenberg
Jun 14, 2002·Annals of Epidemiology·E Claire NewbernJack D Sobel
Mar 3, 2005·Infectious Diseases in Obstetrics and Gynecology·Adriana J PavleticSusan H Polack
Sep 8, 2004·BMC Microbiology·Agata BaczynskaGunna Christiansen
Feb 12, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Goran VujicVedrana Kuzmic Vrbanovic
Jul 1, 2008·Enfermedades infecciosas y microbiología clínica·Rocío Flores-PazMyriam Arriaga-Alba
Jan 9, 2007·Current Opinion in Microbiology·Grant McClartyDavid E Nelson
Jun 5, 2003·The Journal of Clinical Investigation·Harlan D CaldwellGrant McClarty
Jul 18, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M E FalagasS Athanasiou
Aug 5, 2004·Obstetrics and Gynecology·Mark A KlebanoffWilliam W Andrews
Apr 26, 2018·International Journal of Microbiology·Eliza RanjitPramila Parajuli

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