The Diagnostic and Therapeutic Challenges of Posttraumatic Iris Implantation Cysts: Illustrative Case Presentations and a Review of the Literature

Case Reports in Ophthalmological Medicine
Nandini VenkateswaranHolly B Hindman

Abstract

Posttraumatic iris implantation cysts are rare ocular findings that are often associated with poor visual outcomes. Iris implantation cysts can present clinicians with diagnostic and therapeutic challenges given their variable presentations and frequently destructive nature. In this paper, we provide descriptions of two unusual cases of posttraumatic iris implantation cysts. The first case is of a recurrent keratin-filled iris implantation cyst that developed after open globe injury and intraocular implantation of cilia and was treated with cyst debulking procedures, injections of 5-Fluorouracil, and iridocyclectomy. The second case is of recurrent posttraumatic serous iris implantation cysts that were treated with laser, cyst aspiration, and injections of 5-Fluorouracil. We use these cases as a platform to discuss the different manifestations of implantation cysts, the roles of anterior segment optical coherence tomography, ultrasound biomicroscopy, and histopathology in facilitating timely and accurate diagnosis and review the range of available therapeutic modalities. We discuss conservative treatment approaches, including the novel use of 5-Fluorouracil therapy as an adjunct therapy, as well as more aggressive surgical exci...Continue Reading

References

Jun 1, 1979·Ophthalmology·E S MalbranO Croxato
Jun 1, 1978·American Journal of Ophthalmology·W J StarkH Cupples
Jan 1, 1988·The British Journal of Ophthalmology·C ClaouéD Easty
Feb 1, 1985·Ophthalmology·J SugarM F Goldberg
Jan 1, 1971·American Journal of Ophthalmology·D T Vail
Jan 1, 1967·Archives of Ophthalmology·A P Ferry, M R Naghdi
Jun 1, 1995·Archives of Ophthalmology·P T FingerR Ritch
Oct 1, 1993·Archives of Ophthalmology·M HumayunW R Green
Nov 1, 1993·The British Journal of Ophthalmology·H B HohC Dean-Hart
May 1, 1996·Journal of Cataract and Refractive Surgery·P U Fechner
May 1, 1996·Journal of Cataract and Refractive Surgery·M E John
Jul 15, 1998·Ophthalmology·N LoisP De Potter
Mar 8, 2000·American Journal of Ophthalmology·J KuchenbeckerW Behrens-Baumann
Sep 27, 2000·American Journal of Ophthalmology·S Y ShinW R Green
Mar 3, 2001·American Journal of Ophthalmology·J C TsaiD M O'Day
Apr 5, 2002·American Journal of Ophthalmology·Michael M Lai, Julia A Haller
Aug 15, 2003·Ophthalmology·Zohreh Behrouzi, Aliasghar Khodadoust
Jan 1, 1955·American Journal of Ophthalmology·A B RIZZUTI
Jun 1, 1956·American Journal of Ophthalmology·A E MAUMENEE, C R SHANNON
Nov 1, 1958·A.M.A. Archives of Ophthalmology·E F REGAN
Jan 1, 1964·The British Journal of Ophthalmology·W WILSON
Apr 1, 1955·American Journal of Ophthalmology·D G COGAN
Aug 1, 1960·Archives of Ophthalmology·M J HOGAN, E K GOODNER
Nov 12, 2003·Survey of Ophthalmology·Flavio A Marigo, Paul T Finger
Mar 16, 2005·Archives of Ophthalmology·Wasee TulvatanaSurachai Amaranuntakit
Feb 8, 2007·Drugs·Lekha M AbrahamIgal Leibovitch
Sep 8, 2007·Acta Ophthalmologica Scandinavica·Viney GuptaRamanjit Sihota
Oct 22, 2008·American Journal of Ophthalmology·Charles J PavlinIqbal Ike K Ahmed
Dec 20, 2008·Korean Journal of Ophthalmology : KJO·Jin Hae LeeHyun Seung Kim
Jan 13, 2009·Investigative Ophthalmology & Visual Science·Anne HuhtalaHannu Uusitalo
Feb 1, 2011·Seminars in Ophthalmology·Aparna RaoJerry A Shields
Jan 10, 2012·International Ophthalmology·Huda Al-GhadeerAbdulaziz Al-Awad
May 29, 2012·Current Opinion in Ophthalmology·Irit BaharAllan Slomovic
Dec 12, 2012·Archives of Ophthalmology·Nandini VenkateswaranHolly B Hindman
Feb 16, 2013·JAMA Ophthalmology·Esther S HongWallace L M Alward
Jun 5, 2013·Ophthalmology·Hualei ZhaiXinjie Zang
Apr 12, 2014·JAMA Ophthalmology·Carol L ShieldsJerry A Shields
Oct 25, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jike Song, Hongsheng Bi
Dec 30, 2014·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Sangeeta KuganasanVisvaraja Subrayan
Feb 18, 2015·Clinical & Experimental Ophthalmology·George Y X KongWilliam G Campbell

❮ Previous
Next ❯

Citations

Nov 16, 2019·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Amravi ShahParthopratim Dutta Majumder

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Software Mentioned

AS
OCT

Related Concepts

Related Feeds

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.