The diagnostic performance of CT versus FDG PET-CT for the detection of recurrent pancreatic cancer: a systematic review and meta-analysis

European Journal of Radiology
Lois A DaamenI Q Molenaar

Abstract

Radiologic surveillance after resection of pancreatic ductal adenocarcinoma (PDAC) can provide information on the extent and location of disease recurrence. This systematic review and meta-analysis aims to give an overview of the literature on the diagnostic performance of different imaging modalities for the detection of recurrent disease after surgery for PDAC. A systematic search was performed in PubMed, EMBASE and Cochrane Library up to 20 December 2017. All studies reporting on the diagnostic value of imaging modalities for the detection of local and/or distant disease recurrence during follow-up after resection of PDAC were eligible. Both histologic confirmation of recurrent PDAC and clinical confirmation by disease progression on follow-up imaging were considered as suitable reference standard. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used for critical appraisal of methodological quality. Diagnostic accuracy data were extracted or calculated and presented in forest plots. A bivariate random-effects model was used to calculate pooled estimates of sensitivity and specificity. A total of seven retrospective studies with 333 relevant patients were ultimately eligible for data extraction. Over...Continue Reading

Citations

May 31, 2019·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Vincent P GrootJames R Eshleman
Dec 30, 2020·Cancers·Anthony TurpinPascal Hammel
Aug 10, 2020·Seminars in Nuclear Medicine·Farshad Moradi, Andrei Iagaru
Apr 4, 2021·Journal of Clinical Medicine·Ruth González-GómezAlberto J Schuhmacher
Dec 7, 2019·Seminars in Ultrasound, CT, and MR·Heying DuanAndrei Iagaru
May 27, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·James M Halle-SmithKeith J Roberts
Aug 9, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Dengsai PengYue Chen
Jul 10, 2021·Cancer Treatment Reviews·Stefano PartelliPhilip Poortmans

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