The diagnostic performance of expert dermoscopists vs a computer-vision system on small-diameter melanomas

Archives of Dermatology
Robert J FriedmanHensin Tsao

Abstract

To evaluate the performance of dermoscopists in diagnosing small pigmented skin lesions (diameter </= 6 mm) compared with an automatic multispectral computer-vision system. Blinded comparison study. Dermatologic hospital-based clinics and private practice offices. Patients From a computerized skin imaging database of 990 small (</= 6-mm) pigmented skin lesions, all 49 melanomas from 49 patients were included in this study. Fifty randomly selected nonmelanomas from 46 patients served as a control. Ten dermoscopists independently examined dermoscopic images of 99 pigmented skin lesions and decided whether they identified the lesions as melanoma and whether they would recommend biopsy to rule out melanoma. Diagnostic and biopsy sensitivity and specificity were computed and then compared with the results of the computer-vision system. Dermoscopists were able to correctly identify small melanomas with an average diagnostic sensitivity of 39% and a specificity of 82% and recommended small melanomas for biopsy with a sensitivity of 71% and specificity of 49%, with only fair interobserver agreement (kappa = 0.31 for diagnosis and 0.34 for biopsy). In comparison, in recommending biopsy to rule out melanoma, the computer-vision system ac...Continue Reading

Citations

Mar 20, 2010·International Journal of Biomedical Imaging·Massimo Ferri, Ignazio Stanganelli
Dec 4, 2012·Clinical, Cosmetic and Investigational Dermatology·Cila Herman
Jun 21, 2013·Dermatology Practical & Conceptual·Franziska BrehmerHolger A Haenssle
Feb 28, 2014·International Journal of Biomedical Imaging·Ammara Masood, Adel Ali Al-Jumaily
Apr 2, 2013·Expert Opinion on Medical Diagnostics·Erine A Kupetsky, Laura K Ferris
Jul 18, 2012·Dermatologic Clinics·Laura Korb Ferris, Ryan J Harris
Jul 18, 2012·Dermatologic Clinics·Michele J FarberRobert J Friedman
Mar 1, 2012·Seminars in Cutaneous Medicine and Surgery·Allison T O'Donnell, Caroline C Kim
Nov 6, 2010·Seminars in Cutaneous Medicine and Surgery·Steven Q Wang, Pantea Hashemi
Apr 25, 2009·Journal of the American Academy of Dermatology·Agnessa Gadeliya Goodson, Douglas Grossman
Dec 20, 2008·Clinics in Dermatology·Robert J FriedmanEdward R Heilman
May 12, 2012·Journal of Cutaneous Pathology·Gerardo FerraraCatherine M Stefanato
Nov 19, 2011·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Takashi NagaokaTakayuki Sota
Jan 29, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Peter MohrJohn Paoli
Jun 20, 2014·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Axel HauschildDina Gutkowicz-Krusin
May 20, 2015·Journal of the American Academy of Dermatology·Jordon MarchDouglas Grossman
Oct 28, 2016·Lasers in Surgery and Medicine·Milind RajadhyakshaKishwer S Nehal
Mar 22, 2012·Dermatology : International Journal for Clinical and Investigative Dermatology·R P BraunM Mihm
Nov 11, 2017·Future Oncology·Amanda LevineOrit Markowitz
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Lavinia Ferrante di RuffanoUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Jan 18, 2019·Lasers in Surgery and Medicine·Anna-Marie HoskingDaniel S Gareau
Sep 22, 2010·Melanoma Research·Sherrie J Divito, Laura Korb Ferris
Aug 6, 2013·The British Journal of Dermatology·S SeidenariC Magnoni
Nov 29, 2020·Journal of Biomedical Optics·Daniel S GareauJames G Krueger
Mar 3, 2021·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Gustav Boelsgaard ChristensenKari Nielsen
Jun 12, 2021·Indian Journal of Dermatology, Venereology and Leprology·Varadraj Vasant Pai, Rohini Bhat Pai
Apr 15, 2020·Journal of the American Academy of Dermatology·A Nikolas MacLellanRichard G Langley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.