The diagnostic reading of normal level of arterial pressure: metabolism, humoral mediators, biological functions and biological reactions, local pools of inter-cellular medium

Klinicheskaia laboratornaia diagnostika
V N Titov

Abstract

The physiological level of arterial pressure confirms absence in vivo of disorders of biological functions of homeostasis, tropology, endoecology, (biological reactions of excretion and inflammation) and adaptation (biological reactions of compensation and stress). The standard arterial pressure reflects physiological permeability of biolayer (endothelium/pneumocytes and endothelium/trophoblasts) on the interface of common and local pools of inter-cellular medium. Under development of increasing of metabolic arterial pressure it is a non-simple clinical biochemical task to establish which particular function out of four ones has no local compensation at the second level of regulation of metabolism (in paracrine regulating cenosises of cells and organs) and requires such a compensation as increasing of arterial pressure from the third level of regulation of metabolism, from level of organism, vasomotor center of brain. The clinical biochemical differential diagnostic of metabolic arterial hypertension requires new methods of diagnostic. These methods will be based on a mode of quantitative and qualitative detection of analytes in urine known as metabolomics. This is a mode of fluid chromatography of small numerous water-soluble ...Continue Reading

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