The diagnostic value of complete blood count parameters in patients with subarachnoid hemorrhage

Turkish Journal of Emergency Medicine
Turgay Yilmaz KilicMahmut Çamlar

Abstract

Diagnosis of subarachnoid hemorrhage (SAH) in patients presenting with headache is challenging and there has been any biomarker studied for excluding of SAH in those patients. We aim to determine the sensitivity of leukocytosis or left shift to exclude the diagnosis of SAH in ED patients presenting with headache. Adult patients with headache who received a computed tomography (CT) with the diagnosis of SAH and had a complete blood count (CBC) represent the case group, headache patients with normal CT and had a CBC represent the control group. The white blood cell (WBC) count and percentage of polymorphonuclear cells (PMNs%) taken during admission and within the first 6 and 12 h of admission were recorded. A hundred ninety seven patients with SAH and 197 patients without SAH were enrolled in to study. Sensitivity, specificity, NPV and PPV of leukocytosis or increase in PMNs% (left shift) in the diagnosis of SAH was 89.8% (84.5-93.5, 95% CI), 46.7% (39.6-53.9, 95% CI), 82.1% (73.5-88.4, 95% CI) and 62.8% (56.8-68.4, 95% CI) respectively on initial emergency department (ED) admission. CBC should be considered as a noninvasive test for the exclusion of SAH in ED patients with 6 h observation.

References

Feb 1, 1984·Surgical Neurology·D Parkinson, S Stephensen
Dec 25, 2007·The Journal of Emergency Medicine·Jonathan A EdlowChristopher S Ogilvy
Mar 22, 2008·Journal of Neurology·José M FerroR Peralta
Sep 24, 2008·Annals of Emergency Medicine·Jonathan A EdlowUNKNOWN American College of Emergency Physicians
Dec 17, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Khalid A HanafyNeeraj Badjatia
Jun 19, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Wei SunMichael L James
Oct 4, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Andre D KumarSheryl Martin-Schild
Jan 29, 2013·The Journal of Emergency Medicine·Ali FarzadMichael D Witting
Sep 26, 2013·The Journal of Emergency Medicine·Nadine A YoussefScott G Weiner

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