The diagnostic value of the D-xylose absorption test in adult coeliac disease

Scandinavian Journal of Gastroenterology
S Bodé, E Gudmand-Høyer


The 25-g D-xylose absorption test was assessed in a total of 40 adult patients with coeliac disease before and after treatment and in 25 control patients. Because of a large overlap neither the urinary excretion rates nor the 1-h blood concentrations were of any use in the assessment of the individual patients. The overlap was most pronounced for the urine values. In contrast to an earlier report, we could not demonstrate an increased discrimination when the blood concentrations were corrected to a constant body surface area. The D-xylose absorption test provides very little guidance in determining the effect of dietary treatment in coeliac disease. Our results emphasize the serious limitations of the test, and we recommend that it be abandoned.


Feb 1, 1975·American Journal of Clinical Pathology·E L Krawitt, W L Beeken
Jan 1, 1977·Journal of Clinical Pathology·F M StevensC F McCarthy
May 1, 1978·The Journal of Pediatrics·J P ButsA Bonin
Jan 1, 1975·Archives of Disease in Childhood·S P LamabadusuriyaJ T Harries
Jul 28, 1973·British Medical Journal·G E Sladen, P J Kumar
Jan 1, 1982·Transactions of the Royal Society of Tropical Medicine and Hygiene·R D MontgomeryE Clippinger
Nov 1, 1980·The American Journal of Clinical Nutrition·J R Kraut, J D Lloyd-Still
Feb 21, 1957·The New England Journal of Medicine·J A BENSONE BOUGAS
Sep 1, 1959·The American Journal of Medicine·P A CHRISTIANSENJ ABLAZA
Mar 1, 1960·Gut·D FOWLER, W T COOKE
Apr 7, 1962·British Medical Journal·I CHANARIN, M C BENNETT
Oct 1, 1962·The American Journal of Digestive Diseases·I T BECKU CALLEGARINI
Oct 1, 1963·Archives of Disease in Childhood·D HUBBLE, S LITTLEJOHN
Mar 1, 1964·Journal of Clinical Pathology·R A JOSKE, L J HAAGENSEN
Sep 1, 1964·Annals of Internal Medicine·J M FINLAYK J WIGHTMAN


Sep 22, 1988·The New England Journal of Medicine·F Shanahan, W M Weinstein
Sep 9, 1999·Journal of Clinical Gastroenterology·R M Craig, E D Ehrenpreis
Jun 22, 2001·Journal of Clinical Gastroenterology·E D EhrenpreisR M Craig
Oct 1, 1996·Digestive Diseases and Sciences·F CasellasJ R Malagelada
Sep 1, 1988·Scandinavian Journal of Gastroenterology·J P MilnesT S Low-Beer
Jan 1, 1996·Scandinavian Journal of Gastroenterology·S Bodé, E Gudmand-Høyer
Sep 25, 2007·Scandinavian Journal of Gastroenterology·Kari TveitoViggo Skar
Apr 20, 1989·The New England Journal of Medicine
Jul 16, 2010·Scandinavian Journal of Gastroenterology·Kari TveitoViggo Skar
Feb 1, 1991·Digestive Diseases and Sciences·Y PeledT Gilat
Nov 1, 1994·Digestive Diseases and Sciences·F Casellas, J R Malagelada

Related Concepts

Celiac Disease
Clinical Enzyme Tests (Procedure)

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Computational Methods for Protein Structures

Computational methods employing machine learning algorithms are powerful tools that can be used to predict the effect of mutations on protein structure. This is important in neurodegenerative disorders, where some mutations can cause the formation of toxic protein aggregations. This feed follows the latests insights into the relationships between mutation and protein structure leading to better understanding of disease.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.