PMID: 7082388Jan 1, 1982Paper

The dielectric method of investigating bound water in biological material: an appraisal of the technique

E H Grant


Three independent dielectric methods for the measurement of water of hydration (bound water) in a biological material are described and discussed comparatively. For well-defined aqueous solutions of biological molecules, hydration can be obtained from direct observations made on the delta dispersion or from measurement of the dielectric values of the beta dispersion. For whole tissue, however, neither of these two methods is applicable, and to deduce the hydration, it is necessary to use the third technique in which the volume of the hydrated biological particle is obtained by measuring the effect of it on the known dielectric properties of pure water. The hydration can then be calculated by deducting the volume of the anhydrous particle from the experimentally determined volume of the hydrated particle. Owing to possible systemmatic errors the uncertainty in the absolute hydration value associated with this technique is rather larger than that obtained with the other two dielectric methods. For studying the differences between hydration in similar tissues, however, this objection disappears.


Dec 30, 1977·Annals of the New York Academy of Sciences·C G EssexJ Slack
Nov 1, 1979·Physics in Medicine and Biology·K R FosterH P Schwan
Nov 1, 1977·Physics in Medicine and Biology·C G EssexH Peeters
Aug 1, 1969·The Journal of Physical Chemistry·B E Pennock, H P Schwan
Jan 1, 1981·Physics in Medicine and Biology·A W DawkinsE H Grant


Nov 5, 2002·Bioelectrochemistry·M SchaeferM M Gebhard
Apr 13, 2007·Bioelectromagnetics·S I Alekseev, M C Ziskin
Jan 29, 2008·Bioelectromagnetics·S I AlekseevM C Ziskin
Oct 12, 2007·Bioelectromagnetics·S I AlekseevM C Ziskin
Oct 22, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S I AlekseevM C Ziskin
May 1, 1983·The British Journal of Radiology·J A RogersD J Honess
Oct 23, 2017·The Journal of Chemical Physics·Sayantan MondalBiman Bagchi
Dec 6, 2017·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Rajib Biswas, Biman Bagchi

Related Concepts

Body Water
Hydrogen Bonding
Lens, Crystalline

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.