PMID: 2512165Nov 1, 1989Paper

The DiGeorge sequence. II. Immunologic findings in partial and complete forms of the disorder

European Journal of Pediatrics
W MüllerC H Rieger

Abstract

We present immunological in vitro data on a group of 16 patients with the DiGeorge sequence (DGS). Detailed tests gave evidence that the decrease in number and function of mature T-cells is closely correlated with phenotypic expression and represents a wide immunological spectrum ranging from normal function to severe combined immunodeficiency with B-cells. Careful immunological testing in DGS may help to plan therapeutic procedures (i.e. thymic factor therapy or bone marrow transplantation), may also have prognostic significance and help to gain insight into mechanisms operative in disturbances of T-cell regulation.

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Citations

Oct 23, 1995·American Journal of Medical Genetics·D M McDonald-McGinnJ Rome
May 1, 1996·Circulation·B F CuneoD A Driscoll
May 17, 2002·European Journal of Pediatrics·Maria Segni, Donald Zimmerman
Sep 6, 1996·American Journal of Medical Genetics·S A RasmussenR T Zori
Aug 11, 1998·Clinical and Experimental Immunology·S GuptaT Nguyen
Jul 11, 2000·Clinical and Experimental Immunology·M PierdominiciF Pandolfi
Jul 19, 2006·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·A FinocchiC Cancrini
Oct 16, 1999·The New England Journal of Medicine·M L MarkertB F Haynes
Mar 15, 2002·Current Allergy and Asthma Reports·K E Sullivan
Jun 13, 2002·British Journal of Haematology·Danièle BensoussanPierre Bordigoni
Oct 1, 1993·Journal of Medical Genetics·F Greenberg
Nov 1, 1994·European Journal of Pediatrics·A Levy-MozziconacciN Philip
Jan 14, 2010·Journal of Spinal Disorders & Techniques·Athanasios I TsirikosMichael J McMaster

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