The direct catalytic asymmetric aldol reaction of α-substituted nitroacetates with aqueous formaldehyde under base-free neutral phase-transfer conditions

Organic & Biomolecular Chemistry
Seiji ShirakawaKeiji Maruoka

Abstract

Enantioselective direct aldol reaction of α-substituted nitroacetates with aqueous formaldehyde for the synthesis of α-alkyl serines has been achieved under base-free neutral phase-transfer conditions with a bifunctional chiral phase-transfer catalyst.

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Citations

Jun 19, 2012·Organic & Biomolecular Chemistry·Dieter Enders, Thanh Vinh Nguyen
Jan 13, 2016·Organic & Biomolecular Chemistry·Shiho KanekoSeiji Shirakawa
May 31, 2018·Chemical Society Reviews·Yasuhiro YamashitaShū Kobayashi
Apr 1, 2015·Angewandte Chemie·Karin WeidnerMasakatsu Shibasaki
Mar 2, 2013·Angewandte Chemie·Seiji Shirakawa, Keiji Maruoka
Apr 17, 2014·Chemistry, an Asian Journal·Seiji ShirakawaKeiji Maruoka
Jun 23, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Sara Meninno, Alessandra Lattanzi
Nov 20, 2016·Chemistry : a European Journal·Antonin ClemenceauJieping Zhu
Apr 8, 2014·Organic & Biomolecular Chemistry·Hui-Jing LiYan-Chao Wu
Feb 8, 2014·Journal of the American Chemical Society·Barry M Trost, Frédéric Miege
Dec 17, 2014·The Journal of Organic Chemistry·Alison E Metz, Marisa C Kozlowski
Nov 6, 2014·Organic Letters·Golipalli Ramana ReddySridhar Rajaram
Sep 14, 2017·The Journal of Organic Chemistry·Maheswara Rao GokadaSophie Rees-Jones
Dec 19, 2019·The Journal of Organic Chemistry·Yuya ArakiAkira Sakakura

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