PMID: 6399250Jan 1, 1984Paper

The direct effects of compliance on health outcome

Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
L H Epstein

Abstract

Six studies that randomized patients to drugs versus placebo and also made complaint/noncompliant determinations were reviewed to document the main effects of compliance on health outcome. While the studies varied in terms of demonstrating a main effect of drugs, in five of six cases a main statistical effect of compliance was observed. Possible mechanisms for this effect are briefly noted.

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