The discovery of hypothermic neural rescue therapy for perinatal hypoxic-ischemic encephalopathy.

Seminars in Pediatric Neurology
A David Edwards

Abstract

The development of the concepts of delayed post-ischaemic neuronal death and neural rescue brought about a search for clinical treatments to reduce brain damage after birth asphyxia. Cooling had long been an unproven empyrical therapy, and a 20 year programme of careful laboratory and clinical research has proved that hypothermia reduces neurological damage in infants suffering perinatal asphyxial encephalopathy.

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Citations

Jul 21, 2010·Neurotoxicity Research·Mario Herrera-MarschitzPeter J Gebicke-Haerter
Jun 24, 2010·Early Human Development·Dorottya Kelen, Nicola J Robertson
Dec 3, 2014·Seminars in Fetal & Neonatal Medicine·Paolo MontaldoSudhin Thayyil
Apr 26, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·J BenderF Overly

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