The disease presentation of Moyamoya angiopathy in Eastern India

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Shambaditya DasMarkus Kraemer

Abstract

Clinical spectrum of Moyamoya angiopathy (MMA) differs across populations with different ethnicity. This study, the largest one done among Indian population was undertaken to assess clinico-radiological profile of MMA patients in eastern India. A single centre cross-sectional study was undertaken among 76 MMA cases. Each patient was evaluated for epidemiological, clinical and radiological characteristics. SPSS 25 was used for statistical analysis. P < 0.05 was taken as statistically significant. 36 (47.4%) were children without gender preponderance. There were female predominance among adults (male:female = 1:2.33). Mean age at onset of first neurological symptoms for children was 4.2 ± 2.0years, followed by 34.9 ± 58.2months of latency with final diagnosis at the mean age of 7.4 ± 3.5years. For adults, mean age of onset of first neurological symptoms was 31.5 ± 12.3years, followed by 14.7 ± 41.7months time gap and diagnosed at the mean age of 33.5 ± 12.5years. There was a statistically significant difference between child and adult regarding the diagnostic latency (p = 0.035). Fixed motor weakness (FMW) was the predominant symptom across the whole disease course. Among children predominant first neurological symptom was fixed ...Continue Reading

Citations

Jan 29, 2021·BMJ Case Reports·Shambaditya DasBiman Kanti Ray
Apr 18, 2021·Annals of Hematology·Shambaditya DasBiman Kanti Ray
Jul 6, 2021·Clinical Neurology and Neurosurgery·Shambaditya DasMarkus Kraemer
Jul 10, 2021·Journal of Neurology·Sara Pilgram-PastorMarkus Kraemer
Oct 11, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ritwik GhoshJulián Benito-León

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