journal cover

The disposition of coralyne sulphoacetate in rodents

Xenobiotica; the Fate of Foreign Compounds in Biological Systems

May 1, 1976

J PlowmanR H Adamson

Abstract

1. The disposition of (14C) coralyne sulphoacetate has been examined in the mouse and rat at three dose levels. 2. In both species the major route of excretion is biliary following either intraperitoneal or intravenous administration. In rats, 18-24% of the 14C is eliminated in the bile...read more

Mentioned in this Paper

Route of Excretion [PK]
Urine
Large Intestine
Coralyne
Intravenous Injections
Injections, Intraperitoneal
Feces
Metabolite
Rodent
Urine - SpecimenType
Paper Details
References
  • References1
  • Citations1
1
  • References1
  • Citations1
1

Related Papers

Journal of Pharmaceutical Sciences

Solubilization and stabilization of the cytotoxic agent coralyne

Journal of Pharmaceutical SciencesNovember 1, 1975
M J ChoI H Pitman
Journal of Pharmaceutical Sciences

Fluorometric assay for measuring biological half-life of coralyne sulfoacetate in dogs and monkeys

Journal of Pharmaceutical SciencesSeptember 1, 1978
J M Finkel, D L Hill
© 2020 Meta ULC. All rights reserved

The disposition of coralyne sulphoacetate in rodents

Xenobiotica; the Fate of Foreign Compounds in Biological Systems

May 1, 1976

J PlowmanR H Adamson

PMID: 936648

DOI: 10.3109/00498257609151640

Abstract

1. The disposition of (14C) coralyne sulphoacetate has been examined in the mouse and rat at three dose levels. 2. In both species the major route of excretion is biliary following either intraperitoneal or intravenous administration. In rats, 18-24% of the 14C is eliminated in the bile...read more

Mentioned in this Paper

Route of Excretion [PK]
Urine
Large Intestine
Coralyne
Intravenous Injections
Injections, Intraperitoneal
Feces
Metabolite
Rodent
Urine - SpecimenType

Related Papers

Journal of Pharmaceutical Sciences

Solubilization and stabilization of the cytotoxic agent coralyne

Journal of Pharmaceutical SciencesNovember 1, 1975
M J ChoI H Pitman
Journal of Pharmaceutical Sciences

Fluorometric assay for measuring biological half-life of coralyne sulfoacetate in dogs and monkeys

Journal of Pharmaceutical SciencesSeptember 1, 1978
J M Finkel, D L Hill
Paper Details
References
  • References1
  • Citations1
1
  • References1
  • Citations1
1
/papers/the-disposition-of-coralyne-sulphoacetate-in/936648