The distinct morphogenic states of Candida albicans

Trends in Microbiology
Peter SudberyJudith Berman

Abstract

The human fungal pathogen, Candida albicans can grow in at least three different morphologies: yeast, pseudohyphae and hyphae. Further morphological forms exist during colony switching, for example, opaque phase cells are oblong, rather than the oval shape of yeast cells. Pseudohyphae and hyphae are both elongated and sometimes there has been little attempt to distinguish between them, as both are "filamentous forms" of the fungus. We review here the differences between them that suggest that they are distinct morphological states. We argue that studies on "filamentous forms" should always include a formal analysis to determine whether the cells are hyphae or pseudohyphae and we suggest some simple experimental criteria that can be applied to achieve this.

References

Jul 31, 1992·Science·C J Gimeno, G R Fink
Nov 1, 1989·Journal of General Microbiology·L A Merson-Davies, F C Odds
Jul 1, 1986·Journal of General Microbiology·J M Anderson, D R Soll
Jan 1, 1985·Critical Reviews in Microbiology·F C Odds
Feb 1, 1983·The Journal of Cell Biology·D R Soll, L H Mitchell
May 1, 1995·The Journal of Cell Biology·D J Lew, S I Reed
Mar 1, 1993·The Journal of Cell Biology·D J Lew, S I Reed
Nov 1, 1996·Molecular Biology of the Cell·R A SiaD J Lew
May 14, 1998·Microbiology·Gregor D GilfillanNeil A R Gow
Sep 7, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M B EdmondR P Wenzel
Oct 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A S KaoR A Hajjeh
Aug 30, 2000·Nature·Y ZhuC C Mundt
Dec 21, 2000·Current Opinion in Microbiology·M Whiteway
Mar 27, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L G MillerJ E Edwards
Dec 4, 2001·Current Opinion in Microbiology·H Liu
Jan 26, 2002·Molecular Biology of the Cell·Idit HazanHaoping Liu
Aug 6, 2002·Current Opinion in Microbiology·Neil A R GowFrank C Odds
Aug 16, 2002·Molecular Biology of the Cell·Amy J Warenda, James B Konopka
Dec 3, 2002·Nature Reviews. Genetics·Judith Berman, Peter E Sudbery
Jan 7, 2004·Journal of Microbiological Methods·Jacob M HornbyKenneth W Nickerson

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Citations

Apr 16, 2014·PloS One·Xiaojiang TanEleftherios Mylonakis
Jun 14, 2013·Medical Mycology·Alena KasperovaMilan Raska
Feb 7, 2014·Molecular Biology of the Cell·David Caballero-Lima, Peter E Sudbery
Jan 25, 2012·Medical Mycology·Patrícia Albuquerque, Arturo Casadevall
Apr 3, 2014·Applied Microbiology and Biotechnology·Gabor NagyGaspar Banfalvi
Apr 3, 2008·Clinical & Developmental Immunology·Ana LaínJosé Pontón
Sep 10, 2011·International Journal of Microbiology·Gary P MoranDerek J Sullivan
Sep 16, 2014·Fungal Genetics and Biology : FG & B·Chang JiaMingchun Li
Jan 12, 2005·Eukaryotic Cell·Bernardo Chapa y LazoPeter Sudbery
Jan 12, 2005·Eukaryotic Cell·Catherine Bachewich, Malcolm Whiteway
Mar 10, 2005·Eukaryotic Cell·Martine BassilanaRobert A Arkowitz
Apr 9, 2005·Molecular Biology of the Cell·Avigail Atir-LandeDaniel Kornitzer
Apr 9, 2005·Molecular Biology of the Cell·Susana García-SánchezAlistair J P Brown
May 13, 2005·Molecular Biology of the Cell·Eric S BensenJudith Berman
Sep 10, 2005·Eukaryotic Cell·Lois M DouglasJames B Konopka
Jun 6, 2006·Applied and Environmental Microbiology·Kenneth W NickersonJacob M Hornby
Oct 13, 2006·Eukaryotic Cell·Victoria BrownMark Johnston
Nov 10, 2006·Molecular Biology of the Cell·Helen Court, Peter Sudbery
Dec 29, 2006·Molecular Biology of the Cell·Francisco J Alvarez, James B Konopka
Jun 8, 2007·Microbiology and Molecular Biology Reviews : MMBR·Subhrajit BiswasAsis Datta
Jan 25, 2008·Molecular Biology of the Cell·Mohua BanerjeeDavid Kadosh
Jan 1, 2009·Proceedings of the National Academy of Sciences of the United States of America·Patricia L CarlisleDavid Kadosh
Jan 9, 2009·Proceedings of the National Academy of Sciences of the United States of America·Robert J Bastidas, Joseph Heitman
Mar 10, 2009·Eukaryotic Cell·Katharina TrunkMartine Raymond
Jul 8, 2009·Infection and Immunity·Sarah E W GrubbMartin H Thornhill

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