The distribution and determinants of mammographic density measures in Western Australian aboriginal women

Breast Cancer Research : BCR
Kirsty McLeanJennifer Stone

Abstract

Mammographic density (MD) is an established risk factor for breast cancer. There are significant ethnic differences in MD measures which are consistent with those for corresponding breast cancer risk. This is the first study investigating the distribution and determinants of MD measures within Aboriginal women of Western Australia (WA). Epidemiological data and mammographic images were obtained from 628 Aboriginal women and 624 age-, year of screen-, and screening location-matched non-Aboriginal women randomly selected from the BreastScreen Western Australia database. Women were cancer free at the time of their mammogram between 1989 and 2014. MD was measured using the Cumulus software. Kolmogorov-Smirnov tests were used to compare distributions of absolute dense area (DA), precent dense area (PDA), non-dense area (NDA) and total breast area between Aboriginal and non-Aboriginal women. General linear regression was used to estimate the determinants of MD, adjusting for age, NDA, hormone therapy use, family history, measures of socio-economic status and remoteness of residence for Aboriginal and non-Aboriginal women separately. Aboriginal women were found to have lower DA and PDA and higher NDA than non-Aboriginal women. Age (p ...Continue Reading

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Citations

Apr 13, 2019·Breast Cancer Research and Treatment·Ellie DarceyJennifer Stone
Aug 6, 2020·Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals·Ellie DarceyJennifer Stone

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Software Mentioned

BreastScreen
BIRADS
Cumulus
Picture Archiving and Communication System

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