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The distribution of deleterious genetic variation in human populations

bioRxiv

May 21, 2014

Kirk E Lohmueller

Abstract

Population genetic studies suggest that most amino-acid changing mutations are deleterious. Such mutations are of tremendous interest in human population genetics as they are important for the evolutionary process and may contribute risk to common disease. Genomic studies over the past ...read more

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Genetic Population Study
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Genetic Studies
Genomics
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Genome
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The distribution of deleterious genetic variation in human populations

bioRxiv

May 21, 2014

Kirk E Lohmueller

PMID: 990005330

DOI: 10.1101/005330

Abstract

Population genetic studies suggest that most amino-acid changing mutations are deleterious. Such mutations are of tremendous interest in human population genetics as they are important for the evolutionary process and may contribute risk to common disease. Genomic studies over the past ...read more

Mentioned in this Paper

Site
Genetic Population Study
Study
Genetic Studies
Genomics
Population Group
Genome
Documented
23
4

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