PMID: 2486046Jan 1, 1989Paper

The distribution of melanocytic naevi in melanoma patients and control subjects

The Australasian Journal of Dermatology
J W KellyD K Ahn

Abstract

A study of 121 melanoma patients and 139 control subjects was conducted among whites to examine and compare the distribution of non-dysplastic and dysplastic naevi and other pigmented lesions in each group. Melanoma patients had a mean of 97 melanocytic naevi which were greater than 2 mm in diameter and controls had a mean of 36 such naevi, while the medians were 58 and 22 respectively (p less than 0.0001). 55% of melanoma patients and 17% of controls had at least one clinically determined dysplastic naevus, and 26% of melanoma patients and 6% of controls had at least 5 dysplastic naevi. Men were found to have more naevi on the trunk than women in both melanoma cases (p = 0.01), and controls (p = 0.005). Dysplastic naevi were most often found on the trunk and were present at this location in 51% of cases and 17% of controls. Melanoma patients and control subjects with dysplastic naevi, when compared to those without these lesions, had larger number of non-dysplastic naevi. Lentigines were more common among melanoma patients that among control subjects (p = 0.02). There were no differences in the number of non-dysplastic naevi among cases with light and dark hair and eyes, or among controls with these characteristics. There also...Continue Reading

References

Sep 1, 1987·Journal of the American Academy of Dermatology·E A HollyS H Chiu
Jun 1, 1986·Journal of the American Academy of Dermatology·J W KellyR W Sagebiel
Mar 1, 1986·Journal of the American Academy of Dermatology·G C RoushJ M Kirkwood
Mar 15, 1985·International Journal of Cancer. Journal International Du Cancer·A GreenV Siskind
Mar 1, 1985·Journal of Epidemiology and Community Health·K R CookeD C Skegg
Nov 5, 1983·Lancet·K H KraemerD Guerry
Dec 1, 1952·A.M.A. Archives of Surgery·G T PACKD M GERBER

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Citations

Apr 1, 1993·Journal of the American Academy of Dermatology·M A TuckerR W Sagebiel
Jul 26, 2008·Annals of Epidemiology·Leslie K DennisJulie A Coughlin
Jan 1, 1992·Clinics in Dermatology·W Bergman, R M Fusaro
Dec 16, 1998·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·A Spatz, M F Avril

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