PMID: 4895222Mar 1, 1969Paper

The dominance of streptomycin sensitivity re-examined

Proceedings of the National Academy of Sciences of the United States of America
L Breckenridge, L Gorini

Abstract

Several aspects of the strA phenotype were studied in strains of Escherichia coli diploid in the strA chromosomal region. It was found that alleles causing different levels of interference with amber suppression can complement each other, the less restrictive effects being predominant. The sensitive strA(+) allele determines two responses to streptomycin: a dominant effect consisting of a sudden, complete, but reversible inhibition of growth, and a recessive effect manifested as cell killing. Both restriction of suppression and inhibition of growth reflect ribosomal involvement in translation.

References

Jan 1, 1966·Cold Spring Harbor Symposia on Quantitative Biology·L GoriniL Breckenridge
May 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·B Low
Jul 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·L LuzzattoD Schlessinger
Jan 14, 1969·Journal of Molecular Biology·R Rosset, L Gorini
Jun 15, 1964·Biochemical and Biophysical Research Communications·M CouturierR Thomas
Apr 14, 1967·Journal of Molecular Biology·B L Brownstein, L J Lewandowski
Sep 15, 1967·Science·L GoriniR A Zimmermann
Jan 1, 1961·Cold Spring Harbor Symposia on Quantitative Biology·L GORINIM BURGER
Jun 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·L GORINI, E KATAJA
Feb 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·A J CLARK, A D MARGULIES

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Citations

Jun 13, 1991·Biochimica Et Biophysica Acta·C BonnyE Stutz
Aug 17, 1983·Biochimica Et Biophysica Acta·R V Carsia, S Malamed
Mar 1, 1972·Antimicrobial Agents and Chemotherapy·P F Sparling, B D Davis
Aug 25, 1973·Journal of Molecular Biology·A E DahlbergN O Kjeldgaard
Feb 14, 1970·Journal of Molecular Biology·P Strigini, L Gorini
Apr 1, 1981·Journal of Bacteriology·J H LeeG Wilcox

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