The Double Hazard of Bleeding and Thrombosis in Hemostasis From a Clinical Point of View: A Global Assessment by Rotational Thromboelastometry (ROTEM)

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Olga Meltem Akay

Abstract

Hemostasis is a complex dynamic process involving bleeding and thrombosis as two end-points. Conventional coagulation tests which are measured in plasma examine only isolated portions of the coagulation cascade, thereby giving no information on important interactions essential to the clinical evaluation of hemostatic function. Thromboelastography (TEG), originally described in 1948 has improved over the decades and become a valuable tool of coagulation testing because of the limitations of standard coagulation tests. TEG is a technique that provides data about the entire coagulation system, from the beginning of clot formation to fibrinolysis, involving both cellular and plasma components of hemostasis. Rotational thromboelastometry (ROTEM) which evolved from TEG technology overcome several limitations of classical TEG while maintaining a good correlation with conventional TEG determination. ROTEM analyses are useful for rapid assessment of global clotting function in various clinical situations including liver transplantation, cardiac surgery, obstetrics, trauma, hemophilia and idiopathic thrombocytopenic purpura. ROTEM has been also reported to be useful in identifying various hypercoagulable conditions including major surger...Continue Reading

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Citations

May 7, 2020·Transfusion·Jay S RavalMichelle S Harkins
Jan 22, 2020·Critical Care : the Official Journal of the Critical Care Forum·Meghan M ChlebowskiPhilip C Spinella
May 13, 2020·Journal of Thrombosis and Thrombolysis·Vittorio PavoniFrancesca Covani Frigieri
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Jun 27, 2021·Journal of Thrombosis and Thrombolysis·Maurizio FattoruttoArnaud Bruyneel
Jun 30, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Mehmet Gökhan GönenliOlga Meltem Akay
May 12, 2021·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Niels Rahe-MeyerRavi Gill
Sep 17, 2021·Journal of Thrombosis and Haemostasis : JTH·Tímea FellerRobert A S Ariёns

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Methods Mentioned

BETA
surgical resection

Software Mentioned

EXTEM
ROTEM
FIBTEM
INTEM

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