PMID: 2505882Jan 1, 1989Paper

The DST and TRH test in bulimia nervosa

The British Journal of Psychiatry : the Journal of Mental Science
A S KaplanG M Brown

Abstract

Abnormal neuroendocrine responses have been found in depression and eating disorders. It remains unclear whether these reflect an underlying shared biology or epiphenomena. To evaluate this further, we conducted the 1 mg DST and the TSH response to 500 micrograms i.v. TRH in normal-weight bulimics and controls. Bulimics (n = 18) demonstrated significantly more DST non-suppression (45%) than controls (18%; n = 20). In the bulimic group, non-suppressors were significantly thinner than suppressors, but did not differ from them on any measure of depression. Bulimics (n = 19) and controls (n = 12) responded similarly without blunting on the TSH response to TRH. These data suggest that DST non-suppression may be related to non-specific variables such as weight. Bulimics do not demonstrate TSH blunting as found in some depressed patients. These tests do not support evidence for a biological link between these disorders.

References

Apr 1, 1978·Psychoneuroendocrinology·G M BrownP G Ettigi
May 21, 1977·Lancet·F Plantey
May 1, 1979·Archives of General Psychiatry·P T LoosenI C Wilson
Aug 1, 1979·Psychological Medicine·G Russell
Mar 1, 1975·The Journal of Clinical Endocrinology and Metabolism·K MaedaH Imura
Mar 1, 1975·The Journal of Clinical Endocrinology and Metabolism·A I VinikB L Pimstone
Mar 1, 1988·Biological Psychiatry·A B LevyW B Malarkey
Mar 1, 1986·Biological Psychiatry·N KiriikeY Kawakita
Mar 1, 1986·The American Journal of Psychiatry·W J SwiftN E Barklage
Sep 1, 1987·Archives of General Psychiatry·B T WalshA H Glassman
Apr 1, 1985·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·S Musisi, P Garfinkel
Jul 1, 1985·The Journal of Nervous and Mental Disease·N PiranM Owens
Aug 1, 1985·Psychiatry Research·M BergerD von Zerssen
Jan 1, 1985·Journal of Psychiatric Research·P D NorrisR L Palmer
Jan 1, 1974·Behavioral Science·L R DerogatisL Covi
Dec 2, 1971·The New England Journal of Medicine·M S AndersonA J Wise
May 1, 1983·The American Journal of Psychiatry·H G PopeD Yurgelun-Todd
Nov 1, 1984·Archives of General Psychiatry·B T WalshA H Glassman
May 1, 1983·The American Journal of Psychiatry·H E GwirtsmanR H Gerner
Jun 1, 1983·Psychiatry Research·J C GarbuttA J Prange
Feb 1, 1983·The British Journal of Psychiatry : the Journal of Mental Science·J I HudsonD Yurgelun-Todd
Feb 1, 1983·The British Journal of Psychiatry : the Journal of Mental Science·P J Cooper, C G Fairburn
Feb 1, 1983·Psychiatry Research·J I HudsonJ C Melby
Aug 1, 1983·Psychiatry Research·J I HudsonD Yurgelun-Todd
Sep 1, 1983·The American Journal of Psychiatry·P CastroA Herchuelz
Dec 1, 1983·Hospital & Community Psychiatry·T R Insel, F K Goodwin
Mar 1, 1984·The American Journal of Psychiatry·H HaC Foley
Jan 1, 1980·The American Journal of Psychiatry·M S GoldR K Davies
Jan 1, 1980·Psychoneuroendocrinology·P T Loosen, A J Prange
Jun 1, 1980·Acta Endocrinologica·A J IsaacsR Bayliss
Jan 1, 1981·Psychoneuroendocrinology·M S GoldD R Sweeney
Mar 1, 1983·The American Journal of Psychiatry·C K EdelsteinL Dornfeld
May 1, 1983·Archives of General Psychiatry·M BergerD von Zersseen
Sep 1, 1980·Archives of General Psychiatry·R C CasperJ M Davis
Sep 1, 1980·Archives of General Psychiatry·P E GarfinkelD M Garner
Mar 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·B J Carroll
Nov 1, 1982·The American Journal of Psychiatry·M RaskindR Barnes
Nov 1, 1982·The American Journal of Psychiatry·M J DewanL F Major
Nov 1, 1982·Archives of General Psychiatry·C M Swartz, F J Dunner
Dec 1, 1980·Life Sciences·J MendlewiczC Robyn
May 1, 1981·The American Journal of Psychiatry·R H Gerner, H E Gwirtsman
Dec 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·S HoltR C Heading

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Citations

Aug 1, 1991·Biological Psychiatry·S H KennedyP E Garfinkel
Mar 15, 1993·Biological Psychiatry·A R SpalterP W Gold
Jan 1, 1996·Archives of Gerontology and Geriatrics·G Valenti, A Fabbo
Jan 1, 1990·International Journal of Psychiatry in Medicine·J J HaggertyC B Nemeroff
Mar 1, 1997·Psychosomatics·S CrowD Kendall
May 12, 2012·Progress in Neuro-psychopharmacology & Biological Psychiatry·Kenneth R BruceGhislaine Badawi
Aug 2, 2003·Acta Psychiatrica Scandinavica·K A GendallC M Bulik
Nov 1, 1989·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·G M Brown
Dec 1, 1990·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·A S Kaplan
Oct 1, 1995·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·P E GarfinkelA S Kaplan

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