The E. coli MinCDE system in the regulation of protein patterns and gradients

Cellular and Molecular Life Sciences : CMLS
Beatrice RammPetra Schwille

Abstract

Molecular self-organziation, also regarded as pattern formation, is crucial for the correct distribution of cellular content. The processes leading to spatiotemporal patterns often involve a multitude of molecules interacting in complex networks, so that only very few cellular pattern-forming systems can be regarded as well understood. Due to its compositional simplicity, the Escherichia coli MinCDE system has, thus, become a paradigm for protein pattern formation. This biological reaction diffusion system spatiotemporally positions the division machinery in E. coli and is closely related to ParA-type ATPases involved in most aspects of spatiotemporal organization in bacteria. The ATPase MinD and the ATPase-activating protein MinE self-organize on the membrane as a reaction matrix. In vivo, these two proteins typically oscillate from pole-to-pole, while in vitro they can form a variety of distinct patterns. MinC is a passenger protein supposedly operating as a downstream cue of the system, coupling it to the division machinery. The MinCDE system has helped to extract not only the principles underlying intracellular patterns, but also how they are shaped by cellular boundaries. Moreover, it serves as a model to investigate how p...Continue Reading

References

Aug 1, 1992·Molecular Microbiology·Thomas AkerlundKurt Nordström
Oct 1, 1969·Journal of Theoretical Biology·L Wolpert
May 1, 1971·Journal of Theoretical Biology·W D Hamilton
Jun 1, 1984·Journal of Bacteriology·E DavieLawrence Rothfield
Oct 30, 1980·Nature·C Nüsslein-Volhard, E Wieschaus
May 9, 1995·Proceedings of the National Academy of Sciences of the United States of America·C R ZhaoLawrence Rothfield
Jul 1, 1996·Molecular Microbiology·X Wang, Joe Lutkenhaus
Sep 26, 1997·Nature·F J NédélecS Leibler
Jan 15, 1998·Nature·Jan Löwe, Linda A Amos
Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·David M Raskin, Piet A J de Boer
Jun 26, 1999·Molecular Microbiology·Itzhak Fishov, Conrad L Woldringh
Oct 9, 1999·Journal of Bacteriology·David M Raskin, Piet A J de Boer
Dec 28, 1999·Proceedings of the National Academy of Sciences of the United States of America·Z HuJoe Lutkenhaus
Nov 4, 2000·Nature Structural Biology·Glenn F KingLawrence Rothfield
Feb 7, 2001·Proceedings of the National Academy of Sciences of the United States of America·X FuLawrence Rothfield
Feb 13, 2001·Microbiology·Sandra Ramirez-ArcosJo-Anne R Dillon
Mar 15, 2001·FEBS Letters·Suzanne C Cordell, Jan Löwe
Apr 4, 2001·The EMBO Journal·C A HalePiet A J de Boer
May 15, 2001·The EMBO Journal·Suzanne C CordellJan Löwe
Oct 18, 2001·The Journal of Cell Biology·T Misteli
Oct 24, 2001·Journal of Bacteriology·T H SzetoGlenn F King
Dec 6, 2001·Proceedings of the National Academy of Sciences of the United States of America·H Meinhardt, Piet A J de Boer
Jan 25, 2002·Biophysical Journal·Karsten Kruse
Mar 12, 2002·Molecular Microbiology·M E Karoui, Jeff Errington
Mar 28, 2002·Journal of Molecular Biology·Detlef D LeipeL Aravind
May 2, 2002·Proceedings of the National Academy of Sciences of the United States of America·Zonglin HuJoe Lutkenhaus
Oct 9, 2002·Microbiology·Thomas AkerlundKurt Nordström
Nov 9, 2002·Proceedings of the National Academy of Sciences of the United States of America·Tim H SzetoGlenn F King
Dec 17, 2002·Proceedings of the National Academy of Sciences of the United States of America·Kyoko SuefujiDebabrata RayChaudhuri
Jan 21, 2003·Journal of Bacteriology·Laura L LacknerPiet A J de Boer
Apr 5, 2003·The Journal of Biological Chemistry·Eugenia MileykovskayaWilliam Dowhan
Jul 29, 2003·The Journal of Biological Chemistry·Tim H SzetoGlenn F King
Oct 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Kerwyn Casey HuangNed S Wingreen
Feb 20, 2004·Journal of Bacteriology·Huaijin Zhou, Joe Lutkenhaus
Nov 24, 2004·Nature Structural & Molecular Biology·Maria A OlivaJan Löwe
Mar 9, 2005·Molecular Microbiology·Sebastien Pichoff, Joe Lutkenhaus
Dec 3, 2005·Nature Reviews. Microbiology·Lawrence RothfieldYu-Ling Shih
Jan 13, 2006·Journal of Molecular Biology·Shun AdachiSota Hiraga
Feb 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·H I AdlerA A Hardigree
Jun 8, 2006·Annual Review of Biochemistry·Katharine A Michie, Jan Löwe
Aug 4, 2006·Proceedings of the National Academy of Sciences of the United States of America·Suckjoon Jun, Bela Mulder
Aug 29, 2006·Journal of Bacteriology·Ahmed TouhamiAndrew D Rutenberg
Nov 7, 2006·Journal of Bacteriology·Daisuke Shiomi, William Margolin
Jun 5, 2007·Molecular Microbiology·Toshiyuki HatanoHironori Niki
Oct 2, 2007·Journal of Bacteriology·Jonathan LivnyMatthew K Waldor
Dec 25, 2007·Nature Reviews. Microbiology·Sheryl S JusticeScott J Hultgren
Feb 23, 2008·Current Biology : CB·Alex DajkovicJoe Lutkenhaus
Feb 23, 2008·Nature Reviews. Molecular Cell Biology·Eric Karsenti
Apr 19, 2008·Science·Masaki OsawaHarold P Erickson
Apr 24, 2008·Molecular Microbiology·Imrich BarákNada Pavlendová
Sep 2, 2008·Biochimica Et Biophysica Acta·Shirley MazorItzhak Fishov
Nov 4, 2008·Molecular Microbiology·Joyce E Patrick, Daniel B Kearns
Nov 18, 2008·Current Biology : CB·Lukasz KozubowskiDaniel J Lew
Apr 17, 2009·Cellular and Molecular Life Sciences : CMLS·Gurunadh R Chichili, William Rodgers
May 30, 2009·The EMBO Journal·Rok LenarcicLeendert W Hamoen
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kumaran S Ramamurthi, Richard Losick
Dec 23, 2009·Molecular Microbiology·Cheng-Wei HsiehYu-Ling Shih
Mar 6, 2010·Science·David F SavagePamela A Silver
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Elisabeth Fischer-FriedrichKarsten Kruse
May 27, 2010·The EMBO Journal·Maria A OlivaJan Löwe
Jun 15, 2010·Journal of Bacteriology·Jennifer R Juarez, William Margolin
Jun 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·Henrik Strahl, Leendert W Hamoen
Jul 27, 2010·Nature Cell Biology·Jerod L PtacinLucy Shapiro
Oct 13, 2010·Proceedings of the National Academy of Sciences of the United States of America·Houman GhasrianiNatalie K Goto
Jan 6, 2011·Molecular Systems Biology·Barbara Di Ventura, Victor Sourjik
Mar 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Lars D Renner, Douglas B Weibel
Apr 26, 2011·Nature Structural & Molecular Biology·Martin LoosePetra Schwille
Oct 25, 2011·Science·Nathan W GoehringStephan W Grill
Nov 8, 2011·Nature Structural & Molecular Biology·Gert BangeIrmgard Sinning
Mar 6, 2012·Biochimica Et Biophysica Acta·Catalin ChimerelDavid K Summers
Apr 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Mark A J RobertsJudith P Armitage
Apr 18, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jaan MännikCees Dekker
Apr 25, 2012·Proceedings of the National Academy of Sciences of the United States of America·Elizabeth A LibbyMark Goulian
Jun 2, 2012·Molecular Microbiology·Kyung-Tae ParkJoe Lutkenhaus
Sep 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jakob SchweizerPetra Schwille
Sep 27, 2012·The Journal of Biological Chemistry·Lars D Renner, Douglas B Weibel
Oct 13, 2012·Current Biology : CB·Nikolaus LeischSilvia Bulgheresi
Dec 4, 2012·Cell·Susan SchlimpertMartin Thanbichler
Mar 14, 2013·Nature Communications·Heather A CarletonJorge E Galán
Jul 16, 2013·The Journal of Biological Chemistry·Víctor M Hernández-RocamoraGermán Rivas
Jul 31, 2013·Nature Reviews. Microbiology·Ann-Christin Lindås, Rolf Bernander
Sep 12, 2013·Molecular Systems Biology·Barbara Di VenturaVictor Sourjik
Oct 15, 2013·Environmental Microbiology·Ariadna MartosPetra Schwille
Dec 10, 2013·Nature Cell Biology·Martin Loose, Timothy J Mitchison
Dec 18, 2013·PLoS Computational Biology·Mike BonnyKarsten Kruse
Feb 26, 2014·Proceedings of the National Academy of Sciences of the United States of America·Anthony G VecchiarelliKiyoshi Mizuuchi
Mar 8, 2014·Nature Communications·Henrik StrahlLeendert W Hamoen
Apr 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Senthil ArumugamPetra Schwille
May 27, 2014·ELife·Hoong Chuin LimChristine Jacobs-Wagner
Jun 17, 2014·Molecular Microbiology·Anthony G VecchiarelliKiyoshi Mizuuchi
Sep 16, 2014·Nature Communications·Nika PendeSilvia Bulgheresi
Dec 17, 2014·Nature Communications·Debnath GhosalJan Löwe
Dec 19, 2014·PLoS Computational Biology·Robert IetswaartMartin Howard
Mar 4, 2015·Proceedings of the National Academy of Sciences of the United States of America·Jan S SchuhmacherGert Bange
Jun 23, 2015·Nature Nanotechnology·Fabai WuCees Dekker
Jul 22, 2015·FEMS Microbiology Reviews·Jan S SchuhmacherGert Bange
Jul 28, 2015·Developmental Cell·Nora KoryTobias C Walther
Aug 14, 2015·Molecular Microbiology·Kyung-Tae ParkJoe Lutkenhaus
Nov 14, 2015·Annual Review of Cell and Developmental Biology·Anjana BadrinarayananMichael T Laub
Dec 8, 2015·Nature Biotechnology·Alexander SchmidtMatthias Heinemann
Jan 29, 2016·MicrobiologyOpen·Jana MakroczyováImrich Barák
Jan 29, 2016·Nature Communications·Sophie NolivosDavid Sherratt
Feb 18, 2016·Proceedings of the National Academy of Sciences of the United States of America·Anthony G VecchiarelliKiyoshi Mizuuchi
Apr 5, 2016·Nature Reviews. Microbiology·Daniel P Haeusser, William Margolin
Jun 10, 2016·Molecular Systems Biology·Fabai WuCees Dekker
Jul 29, 2016·Angewandte Chemie·Katja ZieskePetra Schwille
Aug 27, 2016·Nature Microbiology·Elisa GalliFrançois-Xavier Barre
Nov 26, 2016·ELife·Yaron Caspi, Cees Dekker
Nov 29, 2016·Molecular Microbiology·Joshua S MacCreadyDaniel C Ducat
Jan 13, 2017·Nature·Katarzyna Zaremba-NiedzwiedzkaThijs J G Ettema
Feb 18, 2017·Science·Alexandre W Bisson-FilhoEthan C Garner
Mar 4, 2017·Current Opinion in Microbiology·Tanneke den BlaauwenPetra Anne Levin
May 10, 2017·Developmental Cell·Dominik SchumacherLotte Søgaard-Andersen
Jun 28, 2017·Proceedings of the National Academy of Sciences of the United States of America·Kyung-Tae ParkJoe Lutkenhaus
Aug 5, 2017·Frontiers in Microbiology·André S G LorenzoniDirk-Jan Scheffers
Oct 29, 2017·Plant Physiology·Cheng ChenKatherine W Osteryoung
Dec 22, 2017·Angewandte Chemie·Philipp GlockPetra Schwille
Feb 7, 2018·Anaerobe·Romana ValenčíkováImrich Barák
Feb 8, 2018·The Journal of Biological Chemistry·Kyung-Tae ParkJoe Lutkenhaus
Mar 6, 2018·Current Biology : CB·Martijn WehrensSander J Tans
Apr 11, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jacob HalatekErwin Frey
Apr 11, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lukas Wettmann, Karsten Kruse
Apr 11, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Yang Yang, Min Wu
Apr 19, 2018·Proceedings of the National Academy of Sciences of the United States of America·Jonas DenkErwin Frey
Aug 14, 2018·Journal of Visualized Experiments : JoVE·Beatrice RammPetra Schwille
Sep 28, 2018·Nature Communications·Beatrice RammPetra Schwille
Oct 2, 2018·Angewandte Chemie·Thomas LitschelPetra Schwille
Oct 3, 2018·Proceedings of the National Academy of Sciences of the United States of America·Shishen DuJoe Lutkenhaus
Dec 21, 2018·ACS Synthetic Biology·Philipp GlockPetra Schwille
Feb 23, 2019·PLoS Biology·William K W HoDenis J Headon
May 29, 2019·Molecular Microbiology·James C WalshPaul M G Curmi

Methods Mentioned

BETA
atomic force microscopy
GTPase
two-hybrid
GTPases
environmental stress

Related Concepts

MinD protein, E coli
MinE protein, E coli
MinC protein, E coli
DNA-dependent ATPase
Cell Division Phases
Plasma Membrane
Protoplasm
Cytoskeletal Proteins
Alkalescens-Dispar Group
Cell Surface Proteins

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.